Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.018 0.039 0.178 9.0 -9999.0 0.0 9.0 KIRREL 0.008 0.05 -9999.0 0.0 -0.215 25.0 25.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.018 0.039 -9999.0 0.0 -0.179 9.0 9.0 PLCG1 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.018 0.021 -9999.0 0.0 -0.204 5.0 5.0 WASL 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.03 0.057 -9999.0 0.0 -0.201 22.0 22.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.022 0.051 -9999.0 0.0 -0.232 9.0 9.0 FYN 0.01 0.041 -9999.0 0.0 -0.181 9.0 9.0 mol:Ca2+ 0.038 0.031 -9999.0 0.0 -0.201 2.0 2.0 mol:DAG 0.039 0.031 -9999.0 0.0 -0.202 2.0 2.0 NPHS2 0.018 0.007 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.039 0.031 -9999.0 0.0 -0.202 2.0 2.0 regulation of endocytosis 0.013 0.059 -9999.0 0.0 -0.208 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol 0.027 0.03 -9999.0 0.0 -0.179 3.0 3.0 establishment of cell polarity 0.018 0.039 -9999.0 0.0 -0.178 9.0 9.0 Nephrin/NEPH1/podocin/NCK1-2 0.035 0.062 -9999.0 0.0 -0.19 26.0 26.0 Nephrin/NEPH1/beta Arrestin2 0.015 0.06 -9999.0 0.0 -0.21 4.0 4.0 NPHS1 0.016 0.023 -9999.0 0.0 -0.211 5.0 5.0 Nephrin/NEPH1/podocin 0.006 0.061 -9999.0 0.0 -0.181 9.0 9.0 TJP1 0.01 0.057 -9999.0 0.0 -0.322 15.0 15.0 NCK1 0.002 0.074 -9999.0 0.0 -0.285 32.0 32.0 NCK2 0.012 0.051 -9999.0 0.0 -0.336 11.0 11.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.04 0.032 -9999.0 0.0 -0.202 2.0 2.0 CD2AP 0.004 0.075 -9999.0 0.0 -0.338 24.0 24.0 Nephrin/NEPH1/podocin/GRB2 0.035 0.045 -9999.0 0.0 -0.199 12.0 12.0 GRB2 0.012 0.053 -9999.0 0.0 -0.35 11.0 11.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.018 0.029 -9999.0 0.0 -0.183 2.0 2.0 cytoskeleton organization 0.023 0.05 -9999.0 0.0 -0.238 6.0 6.0 Nephrin/NEPH1 0.017 0.027 -9999.0 0.0 -0.192 2.0 2.0 Nephrin/NEPH1/ZO-1 0.024 0.049 -9999.0 0.0 -0.219 13.0 13.0