Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.06 0.148 -9999.0 0.0 -0.295 124.0 124.0 MAP3K8 -0.011 0.086 -9999.0 0.0 -0.252 56.0 56.0 FOS -0.033 0.098 -9999.0 0.0 -0.282 26.0 26.0 PRKCA 0.013 0.016 -9999.0 0.0 -0.217 2.0 2.0 PTPN7 0.013 0.014 -9999.0 0.0 -0.226 1.0 1.0 HRAS 0.014 0.04 -9999.0 0.0 -0.27 10.0 10.0 PRKCB -0.005 0.007 -9999.0 0.0 -0.012 233.0 233.0 NRAS -0.031 0.118 -9999.0 0.0 -0.29 87.0 87.0 RAS family/GTP -0.014 0.084 -9999.0 0.0 -0.204 67.0 67.0 MAPK3 -0.0 0.045 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 -0.011 0.055 -9999.0 0.0 -0.194 17.0 17.0 ELK1 0.012 0.016 -9999.0 0.0 -0.231 1.0 1.0 BRAF -0.0 0.032 -9999.0 0.0 -0.158 1.0 1.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 228.0 228.0 MAPK1 -0.023 0.106 -9999.0 0.0 -0.465 23.0 23.0 RAF1 -0.006 0.058 -9999.0 0.0 -0.385 9.0 9.0 KRAS -0.007 0.087 -9999.0 0.0 -0.271 49.0 49.0