Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.001 0.16 -9999.0 0.0 -0.283 85.0 85.0 MAP3K8 0.028 0.036 -9999.0 0.0 -0.025 68.0 68.0 FOS 0.009 0.11 -9999.0 0.0 -0.362 11.0 11.0 PRKCA 0.023 0.029 -9999.0 0.0 -0.029 113.0 113.0 PTPN7 0.024 0.033 -9999.0 0.0 -0.036 111.0 111.0 HRAS 0.034 0.01 -9999.0 0.0 0.0 38.0 38.0 PRKCB -0.001 0.008 0.009 107.0 -0.015 118.0 225.0 NRAS 0.029 0.027 -9999.0 0.0 -0.01 88.0 88.0 RAS family/GTP 0.031 0.071 -9999.0 0.0 -0.157 52.0 52.0 MAPK3 0.031 0.058 -9999.0 0.0 -0.328 3.0 3.0 MAP2K1 0.009 0.071 0.182 1.0 -0.236 17.0 18.0 ELK1 0.021 0.033 -9999.0 0.0 -0.039 117.0 117.0 BRAF 0.005 0.032 -9999.0 0.0 -0.247 3.0 3.0 mol:GTP -0.001 0.002 0.002 23.0 -0.005 118.0 141.0 MAPK1 0.002 0.126 -9999.0 0.0 -0.407 35.0 35.0 RAF1 -0.0 0.056 -9999.0 0.0 -0.331 11.0 11.0 KRAS 0.03 0.014 -9999.0 0.0 0.0 92.0 92.0