MutSigWithNozzleReport Execution Log 11:38 AM Fri May 4, '12

Running as user: cgaadm

MutSigPreprocess1 individual_set_id BLCA
MutSigPreprocess1 maf1 dependentsValues1099751721527743546.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 dependentsValues3460092943680600561.tsv
MutSigPreprocess1 build hg18
MutSigPreprocess1 context65_dir /xchip/cga1/lawrence/db/context65
MutSigPreprocess1 context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 individual_set_id BLCA
MutSigRun3 gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
MutSigRun3 build hg18
MutSigRun3 geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg18
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 jobcount 200
GDAC_MutSig_Report4 ind_set BLCA
Execution Times:
Submitted: 11:38:10 04-05-12
Completed:
Elapsed: 09 hrs 05 mins 57 secs

step 1. MutSigPreprocess [id: 84400] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:63
individual_set_id BLCA
maf1 dependentsValues1099751721527743546.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 dependentsValues3460092943680600561.tsv
wig2
wig3
wig4
build hg18
context65_dir /xchip/cga1/lawrence/db/context65
context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
num_categories 4
target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
Output Files:
 BLCA.mutation_preprocessing_report.txt
 BLCA.maf
 BLCA.coverage.prepare.txt
 BLCA.patients.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 11:38:10 04-05-12
Completed: 11:40:14 04-05-12
Elapsed: 00 hrs 02 mins 04 secs

step 2. ProcessCoverageForMutSig [id: 84401] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:50
coverage_prepare_file BLCA.coverage.prepare.txt
patient_list BLCA.patients.txt
mutation_list BLCA.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 BLCA.covfiles
 BLCA.summed_coverage.fwi
 BLCA.summed_coverage.fwb
 BLCA.mutcateg_discovery.txt
 BLCA.mutcategs.txt
 BLCA.coverage.mat
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 11:38:10 04-05-12
Completed: 13:39:19 04-05-12
Elapsed: 02 hrs 01 mins 09 secs

step 3. MutSigRun [id: 84402] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:120
individual_set_id BLCA
mutation_file BLCA.maf
coverage_file BLCA.coverage.mat
patient_file BLCA.patients.txt
category_file BLCA.mutcategs.txt
gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
build hg18
geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg18
param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
mutation_preprocessing_report_file BLCA.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 BLCA.MutSig_version.txt
 BLCA.mutation_filtering_report.txt
 BLCA.per_exon.coverage.txt
 BLCA.covplot.png
 BLCA.covplot_hires.png
 BLCA.patients.counts_and_rates.txt
 BLCA.bargraphs.png
 BLCA.bargraphs_hires.png
 BLCA.num_patients.txt
 BLCA.final_analysis_set.maf
 BLCA.mutcategs.txt
 BLCA.per_gene.coverage.txt
 BLCA.per_gene.mutation_counts.txt
 BLCA.mutation_breakdown.txt
 BLCA.sample_sig_gene_table.txt
 BLCA.mutation_rates.txt
 BLCA.sig_genes.txt
 BLCA.sig_genesets.txt
 BLCA.sig_genesets_2.txt
 BLCA.cosmic_mutations.txt_verbose.txt
 BLCA.cosmic_sig_genes2.txt
 BLCA.cosmic_mutations.txt
 BLCA.cosmic_sig_genes.txt
 BLCA.gene_gene_correlations.txt
 BLCA.power_per_gene.total_coverage.txt
 BLCA.clustered_muts.txt
 BLCA.power_per_gene.total_coverage_histogram
 BLCA.power_per_gene.power_stats.txt
 BLCA.power_per_gene.power_stats_full.txt
 BLCA.power_per_gene.power_summary.txt
 BLCA.gene_coverage_plots
 sig_genes.txt
 CLM_full.html
 GGC_full.html
 CM_full.html
 patients.counts_and_rates.html
 report.html
 SGS_full.html
 CSG2_full.html
 CSG_full.html
 SGS2_full.html
 SG_full.html
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 11:38:10 04-05-12
Completed: 20:43:50 04-05-12
Elapsed: 09 hrs 05 mins 40 secs

step 4. GDAC_MutSig_Report [id: 84403] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:10
bar_plot BLCA.bargraphs.png
breakdown_table BLCA.mutation_breakdown.txt
categories_table BLCA.mutation_rates.txt
coverage png BLCA.covplot.png
sig_table BLCA.sig_genes.txt
cosmic_table BLCA.cosmic_sig_genes.txt
cosmic_table2 BLCA.cosmic_sig_genes2.txt
cosmic_muts_table BLCA.cosmic_mutations.txt
cluster_table BLCA.clustered_muts.txt
geneset_table BLCA.sig_genesets.txt
genset_table2 BLCA.sig_genesets_2.txt
patients_c_and_r BLCA.patients.counts_and_rates.txt
ind_set BLCA
mutsig_version BLCA.MutSig_version.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 11:38:10 04-05-12
Completed: 20:44:05 04-05-12
Elapsed: 09 hrs 05 mins 55 secs