Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 -0.028 0.16 -9999.0 0.0 -0.584 17.0 17.0 EPHB2 -0.019 0.147 -9999.0 0.0 -0.611 13.0 13.0 EFNB1 0.008 0.084 -9999.0 0.0 -0.356 11.0 11.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.072 0.159 -9999.0 0.0 -0.488 10.0 10.0 Ephrin B2/EPHB1-2 -0.117 0.18 -9999.0 0.0 -0.385 44.0 44.0 neuron projection morphogenesis -0.099 0.128 -9999.0 0.0 -0.467 10.0 10.0 Ephrin B1/EPHB1-2/Tiam1 -0.084 0.17 -9999.0 0.0 -0.527 10.0 10.0 DNM1 0.003 0.082 -9999.0 0.0 -0.491 6.0 6.0 cell-cell signaling -0.001 0.003 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.223 0.313 -9999.0 0.0 -0.654 73.0 73.0 YES1 -0.303 0.408 -9999.0 0.0 -0.914 67.0 67.0 Ephrin B1/EPHB1-2/NCK2 -0.081 0.169 -9999.0 0.0 -0.527 10.0 10.0 PI3K -0.217 0.318 -9999.0 0.0 -0.678 69.0 69.0 mol:GDP -0.084 0.168 -9999.0 0.0 -0.521 10.0 10.0 ITGA2B 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 endothelial cell proliferation -0.018 0.119 -9999.0 0.0 -0.357 24.0 24.0 FYN -0.309 0.412 -9999.0 0.0 -0.899 70.0 70.0 MAP3K7 -0.236 0.329 -9999.0 0.0 -0.717 68.0 68.0 FGR -0.304 0.406 -9999.0 0.0 -0.912 67.0 67.0 TIAM1 0.01 0.067 -9999.0 0.0 -0.561 3.0 3.0 PIK3R1 0.009 0.072 -9999.0 0.0 -0.609 3.0 3.0 RGS3 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.186 0.294 -9999.0 0.0 -0.611 69.0 69.0 LYN -0.302 0.407 -9999.0 0.0 -0.912 67.0 67.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.284 0.381 -9999.0 0.0 -0.854 67.0 67.0 Ephrin B1/EPHB1-2 -0.266 0.348 -9999.0 0.0 -0.781 67.0 67.0 SRC -0.304 0.406 -9999.0 0.0 -0.886 70.0 70.0 ITGB3 0.015 0.032 -9999.0 0.0 -0.466 1.0 1.0 EPHB1 -0.168 0.251 -9999.0 0.0 -0.501 80.0 80.0 EPHB4 -0.002 0.1 -9999.0 0.0 -0.52 8.0 8.0 RAC1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 -0.017 0.12 -9999.0 0.0 -0.359 24.0 24.0 alphaIIb/beta3 Integrin 0.024 0.023 -9999.0 0.0 -0.321 1.0 1.0 BLK -0.307 0.409 -9999.0 0.0 -0.917 67.0 67.0 HCK -0.326 0.418 -9999.0 0.0 -0.879 75.0 75.0 regulation of stress fiber formation 0.081 0.167 0.521 10.0 -9999.0 0.0 10.0 MAPK8 -0.204 0.298 -9999.0 0.0 -0.628 70.0 70.0 Ephrin B1/EPHB1-2/RGS3 -0.08 0.169 -9999.0 0.0 -0.527 10.0 10.0 endothelial cell migration -0.234 0.294 -9999.0 0.0 -0.604 79.0 79.0 NCK2 0.015 0.032 -9999.0 0.0 -0.466 1.0 1.0 PTPN13 -0.283 0.337 -9999.0 0.0 -0.632 104.0 104.0 regulation of focal adhesion formation 0.081 0.167 0.521 10.0 -9999.0 0.0 10.0 chemotaxis 0.08 0.167 0.521 10.0 -9999.0 0.0 10.0 PIK3CA 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP -0.1 0.133 -9999.0 0.0 -0.48 10.0 10.0 angiogenesis -0.264 0.345 -9999.0 0.0 -0.775 67.0 67.0 LCK -0.317 0.415 -9999.0 0.0 -0.917 69.0 69.0