Arf6 downstream pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations PLAUR -0.006 0.213 -9999.0 0.0 -1.153 6.0 6.0 regulation of axonogenesis -0.015 0.077 0.4 5.0 -9999.0 0.0 5.0 myoblast fusion 0.003 0.098 0.396 11.0 -9999.0 0.0 11.0 mol:GTP -0.005 0.081 -9999.0 0.0 -0.343 10.0 10.0 regulation of calcium-dependent cell-cell adhesion -0.021 0.085 0.346 7.0 -9999.0 0.0 7.0 ARF1/GTP 0.01 0.064 -9999.0 0.0 -0.347 5.0 5.0 mol:GM1 -0.002 0.063 -9999.0 0.0 -0.266 10.0 10.0 mol:Choline 0.014 0.075 -9999.0 0.0 -0.316 8.0 8.0 lamellipodium assembly -0.028 0.103 -9999.0 0.0 -0.448 11.0 11.0 MAPK3 0.003 0.103 -9999.0 0.0 -0.342 16.0 16.0 ARF6/GTP/NME1/Tiam1 0.022 0.086 -9999.0 0.0 -0.347 7.0 7.0 ARF1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6/GDP -0.003 0.099 -9999.0 0.0 -0.398 11.0 11.0 ARF1/GDP 0.009 0.092 -9999.0 0.0 -0.358 11.0 11.0 ARF6 -0.004 0.108 -9999.0 0.0 -0.701 5.0 5.0 RAB11A 0.01 0.067 -9999.0 0.0 -0.561 3.0 3.0 TIAM1 0.01 0.067 -9999.0 0.0 -0.557 3.0 3.0 fibronectin binding -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MAPK1 0.012 0.095 -9999.0 0.0 -0.363 11.0 11.0 actin filament bundle formation -0.007 0.091 0.357 11.0 -9999.0 0.0 11.0 KALRN -0.02 0.077 -9999.0 0.0 -0.332 11.0 11.0 RAB11FIP3/RAB11A 0.014 0.079 -9999.0 0.0 -0.495 5.0 5.0 RhoA/GDP 0.007 0.092 -9999.0 0.0 -0.36 11.0 11.0 NME1 0.015 0.042 -9999.0 0.0 -0.607 1.0 1.0 Rac1/GDP 0.007 0.092 -9999.0 0.0 -0.36 11.0 11.0 substrate adhesion-dependent cell spreading -0.005 0.081 -9999.0 0.0 -0.343 10.0 10.0 cortical actin cytoskeleton organization -0.028 0.103 -9999.0 0.0 -0.452 11.0 11.0 RAC1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 liver development -0.005 0.081 -9999.0 0.0 -0.343 10.0 10.0 ARF6/GTP -0.005 0.081 -9999.0 0.0 -0.343 10.0 10.0 RhoA/GTP 0.01 0.064 -9999.0 0.0 -0.347 5.0 5.0 mol:GDP -0.026 0.093 -9999.0 0.0 -0.398 11.0 11.0 ARF6/GTP/RAB11FIP3/RAB11A 0.012 0.095 -9999.0 0.0 -0.434 8.0 8.0 RHOA 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLD1 0.004 0.083 -9999.0 0.0 -0.362 9.0 9.0 RAB11FIP3 0.009 0.072 -9999.0 0.0 -0.609 3.0 3.0 tube morphogenesis -0.028 0.103 -9999.0 0.0 -0.448 11.0 11.0 ruffle organization 0.015 0.077 -9999.0 0.0 -0.4 5.0 5.0 regulation of epithelial cell migration -0.005 0.081 -9999.0 0.0 -0.343 10.0 10.0 PLD2 0.01 0.067 -9999.0 0.0 -0.338 6.0 6.0 PIP5K1A 0.015 0.078 -9999.0 0.0 -0.402 5.0 5.0 mol:Phosphatidic acid 0.014 0.075 -9999.0 0.0 -0.316 8.0 8.0 Rac1/GTP -0.028 0.104 -9999.0 0.0 -0.453 11.0 11.0