Effects of Botulinum toxin Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations STX1A 0.009 0.04 -9999.0 0.0 -0.333 3.0 3.0 UniProt:P19321 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RIMS1/UNC13B 0.019 0.05 -9999.0 0.0 -0.351 4.0 4.0 STXBP1 -0.001 0.097 -9999.0 0.0 -0.502 8.0 8.0 ACh/CHRNA1 0.013 0.039 -9999.0 0.0 -0.291 3.0 3.0 RAB3GAP2/RIMS1/UNC13B 0.026 0.057 -9999.0 0.0 -0.369 3.0 3.0 mol:Ca2+ 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 UniProt:P30996 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 UniProt:Q60393 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CST086 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RIMS1 0.013 0.045 -9999.0 0.0 -0.466 2.0 2.0 mol:ACh 0.007 0.022 -9999.0 0.0 -0.131 4.0 4.0 RAB3GAP2 0.012 0.059 -9999.0 0.0 -0.609 2.0 2.0 STX1A/SNAP25/VAMP2 -0.018 0.061 -9999.0 0.0 -0.463 1.0 1.0 UniProt:P10844 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 muscle contraction 0.013 0.039 -9999.0 0.0 -0.29 3.0 3.0 UNC13B 0.012 0.053 -9999.0 0.0 -0.537 2.0 2.0 CHRNA1 0.011 0.056 -9999.0 0.0 -0.466 3.0 3.0 UniProt:P10845 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ACh/Synaptotagmin 1 -0.114 0.178 -9999.0 0.0 -0.348 80.0 80.0 SNAP25 0.002 0.045 -9999.0 0.0 -0.237 7.0 7.0 VAMP2 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 SYT1 -0.181 0.27 -9999.0 0.0 -0.539 80.0 80.0 UniProt:Q00496 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 STXIA/STXBP1 0.008 0.068 -9999.0 0.0 -0.29 11.0 11.0 STX1A/SNAP25 fragment 1/VAMP2 -0.018 0.061 -9999.0 0.0 -0.463 1.0 1.0