Lissencephaly gene (LIS1) in neuronal migration and development Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations DYNC1H1 0.032 0.011 -9999.0 0.0 -9999.0 0.0 0.0 VLDLR -0.084 0.198 -9999.0 0.0 -0.369 61.0 61.0 LRPAP1 0.035 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NUDC 0.034 0.009 -9999.0 0.0 -9999.0 0.0 0.0 RELN/LRP8 0.047 0.08 -9999.0 0.0 -0.298 9.0 9.0 CaM/Ca2+ 0.024 0.008 -9999.0 0.0 -9999.0 0.0 0.0 KATNA1 0.035 0.006 -9999.0 0.0 -9999.0 0.0 0.0 GO:0030286 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ABL1 0.012 0.07 -9999.0 0.0 -0.271 9.0 9.0 IQGAP1/CaM 0.046 0.019 -9999.0 0.0 -9999.0 0.0 0.0 DAB1 0.035 0.005 -9999.0 0.0 -9999.0 0.0 0.0 IQGAP1 0.034 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G7 -0.05 0.179 -9999.0 0.0 -0.379 43.0 43.0 CALM1 0.032 0.011 -9999.0 0.0 -9999.0 0.0 0.0 DYNLT1 0.035 0.006 -9999.0 0.0 -9999.0 0.0 0.0 mol:Ca2+ -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 LRPAP1/LRP8 0.03 0.084 -9999.0 0.0 -0.349 9.0 9.0 UniProt:Q4QZ09 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CLIP1 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R1 0.035 0.007 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/Poliovirus Protein 3A 0.01 0.007 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R2 0.036 0.002 -9999.0 0.0 -9999.0 0.0 0.0 mol:PP1 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1 -0.015 0.136 -9999.0 0.0 -0.298 32.0 32.0 YWHAE 0.03 0.013 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1/14-3-3 E 0.026 0.075 0.333 3.0 -9999.0 0.0 3.0 MAP1B 0.005 0.018 0.182 1.0 -9999.0 0.0 1.0 RAC1 0.013 0.01 -9999.0 0.0 -9999.0 0.0 0.0 p35/CDK5 0.018 0.063 -9999.0 0.0 -0.244 9.0 9.0 RELN 0.033 0.018 -9999.0 0.0 -0.204 1.0 1.0 PAFAH/LIS1 -0.013 0.099 -9999.0 0.0 -0.29 20.0 20.0 LIS1/CLIP170 0.01 0.007 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/NDEL1/Katanin 60/Dynein Light chain/Dynein heavy chain 0.02 0.062 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1/LIS1/PAFAH1B2/PAFAH1B3 -0.016 0.121 -9999.0 0.0 -0.264 33.0 33.0 GO:0005869 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1 0.013 0.07 0.331 3.0 -9999.0 0.0 3.0 LIS1/IQGAP1 0.028 0.019 -9999.0 0.0 -9999.0 0.0 0.0 RHOA 0.014 0.01 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B1 0.013 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B3 0.033 0.036 -9999.0 0.0 -0.483 1.0 1.0 PAFAH1B2 0.03 0.043 -9999.0 0.0 -0.297 3.0 3.0 MAP1B/LIS1/Dynein heavy chain 0.018 0.04 -9999.0 0.0 -0.252 1.0 1.0 NDEL1/Katanin 60/Dynein heavy chain 0.033 0.087 0.354 4.0 -9999.0 0.0 4.0 LRP8 0.009 0.109 -9999.0 0.0 -0.413 12.0 12.0 NDEL1/Katanin 60 0.019 0.08 0.333 3.0 -9999.0 0.0 3.0 P39/CDK5 0.02 0.064 -9999.0 0.0 -0.244 9.0 9.0 LIS1/NudC/Dynein intermediate chain/microtubule organizing center 0.028 0.019 -9999.0 0.0 -9999.0 0.0 0.0 CDK5 -0.017 0.06 0.187 5.0 -0.255 9.0 14.0 PPP2R5D 0.034 0.017 -9999.0 0.0 -0.204 1.0 1.0 LIS1/CLIP170/Dynein Complex/Dynactin Complex 0.009 0.006 -9999.0 0.0 -9999.0 0.0 0.0 CSNK2A1 0.028 0.015 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1/LIS1 0.006 0.128 -9999.0 0.0 -0.256 29.0 29.0 RELN/VLDLR -0.017 0.145 -9999.0 0.0 -0.273 41.0 41.0 CDC42 0.013 0.013 -9999.0 0.0 -9999.0 0.0 0.0