Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.053 0.018 -9999.0 0.0 -9999.0 0.0 0.0 KIRREL 0.038 0.009 -9999.0 0.0 -0.041 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.053 0.018 -9999.0 0.0 -9999.0 0.0 0.0 PLCG1 0.035 0.007 -9999.0 0.0 0.0 20.0 20.0 ARRB2 0.034 0.008 -9999.0 0.0 0.0 27.0 27.0 WASL 0.025 0.017 -9999.0 0.0 0.0 155.0 155.0 Nephrin/NEPH1/podocin/CD2AP 0.081 0.049 -9999.0 0.0 -0.122 15.0 15.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.015 0.034 -9999.0 0.0 -0.194 6.0 6.0 FYN -0.005 0.049 0.174 30.0 -9999.0 0.0 30.0 mol:Ca2+ 0.084 0.036 -9999.0 0.0 -0.125 3.0 3.0 mol:DAG 0.086 0.037 -9999.0 0.0 -0.126 3.0 3.0 NPHS2 0.039 0.008 -9999.0 0.0 -0.041 1.0 1.0 mol:IP3 0.086 0.037 -9999.0 0.0 -0.126 3.0 3.0 regulation of endocytosis 0.051 0.05 -9999.0 0.0 -0.136 5.0 5.0 Nephrin/NEPH1/podocin/Cholesterol 0.068 0.027 -9999.0 0.0 -9999.0 0.0 0.0 establishment of cell polarity 0.053 0.018 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2 0.093 0.058 -9999.0 0.0 -0.137 16.0 16.0 Nephrin/NEPH1/beta Arrestin2 0.053 0.052 -9999.0 0.0 -0.138 5.0 5.0 NPHS1 0.038 0.011 0.076 6.0 -9999.0 0.0 6.0 Nephrin/NEPH1/podocin 0.051 0.044 -9999.0 0.0 -0.107 1.0 1.0 TJP1 0.034 0.009 -9999.0 0.0 0.0 34.0 34.0 NCK1 0.034 0.008 -9999.0 0.0 0.0 26.0 26.0 NCK2 0.035 0.007 -9999.0 0.0 0.0 19.0 19.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.087 0.037 -9999.0 0.0 -0.126 3.0 3.0 CD2AP 0.033 0.01 -9999.0 0.0 0.0 43.0 43.0 Nephrin/NEPH1/podocin/GRB2 0.086 0.04 -9999.0 0.0 -0.131 5.0 5.0 GRB2 0.035 0.006 -9999.0 0.0 0.0 16.0 16.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.011 0.054 0.173 33.0 -9999.0 0.0 33.0 cytoskeleton organization -0.01 0.03 0.203 4.0 -0.204 2.0 6.0 Nephrin/NEPH1 0.045 0.015 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/ZO-1 0.063 0.037 -9999.0 0.0 -0.14 8.0 8.0