Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 -0.066 0.229 -9999.0 0.0 -0.667 9.0 9.0 EPHB2 0.019 0.002 -9999.0 0.0 -9999.0 0.0 0.0 EFNB1 -0.056 0.203 -9999.0 0.0 -0.463 13.0 13.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.081 0.162 -9999.0 0.0 -0.52 4.0 4.0 Ephrin B2/EPHB1-2 -0.047 0.184 -9999.0 0.0 -0.497 8.0 8.0 neuron projection morphogenesis -0.086 0.149 -9999.0 0.0 -0.497 4.0 4.0 Ephrin B1/EPHB1-2/Tiam1 -0.056 0.196 -9999.0 0.0 -0.439 11.0 11.0 DNM1 -0.053 0.195 -9999.0 0.0 -0.565 9.0 9.0 cell-cell signaling -0.001 0.002 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 0.006 0.156 -9999.0 0.0 -0.909 2.0 2.0 YES1 -0.027 0.187 -9999.0 0.0 -1.133 2.0 2.0 Ephrin B1/EPHB1-2/NCK2 -0.039 0.185 -9999.0 0.0 -0.465 8.0 8.0 PI3K -0.023 0.232 -9999.0 0.0 -0.755 5.0 5.0 mol:GDP -0.057 0.193 -9999.0 0.0 -0.434 11.0 11.0 ITGA2B 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 endothelial cell proliferation -0.03 0.15 -9999.0 0.0 -0.423 9.0 9.0 FYN -0.057 0.221 -9999.0 0.0 -1.311 2.0 2.0 MAP3K7 -0.024 0.161 -9999.0 0.0 -0.971 2.0 2.0 FGR -0.027 0.187 -9999.0 0.0 -1.129 2.0 2.0 TIAM1 -0.01 0.145 -9999.0 0.0 -0.708 3.0 3.0 PIK3R1 -0.038 0.194 -9999.0 0.0 -0.677 6.0 6.0 RGS3 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.025 0.228 -9999.0 0.0 -0.943 3.0 3.0 LYN -0.027 0.187 -9999.0 0.0 -1.133 2.0 2.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.03 0.184 -9999.0 0.0 -1.114 2.0 2.0 Ephrin B1/EPHB1-2 -0.031 0.172 -9999.0 0.0 -1.045 2.0 2.0 SRC -0.027 0.187 -9999.0 0.0 -1.129 2.0 2.0 ITGB3 -0.03 0.169 -9999.0 0.0 -0.585 6.0 6.0 EPHB1 -0.041 0.171 -9999.0 0.0 -0.523 8.0 8.0 EPHB4 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAC1 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 -0.03 0.151 -9999.0 0.0 -0.425 9.0 9.0 alphaIIb/beta3 Integrin -0.008 0.126 -9999.0 0.0 -0.419 6.0 6.0 BLK -0.03 0.189 -9999.0 0.0 -1.144 2.0 2.0 HCK -0.033 0.191 -9999.0 0.0 -1.144 2.0 2.0 regulation of stress fiber formation 0.039 0.183 0.46 8.0 -9999.0 0.0 8.0 MAPK8 0.016 0.147 -9999.0 0.0 -0.851 2.0 2.0 Ephrin B1/EPHB1-2/RGS3 -0.039 0.185 -9999.0 0.0 -0.465 8.0 8.0 endothelial cell migration -0.063 0.201 -9999.0 0.0 -0.547 8.0 8.0 NCK2 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 -0.012 0.143 -9999.0 0.0 -0.854 2.0 2.0 regulation of focal adhesion formation 0.039 0.183 0.46 8.0 -9999.0 0.0 8.0 chemotaxis 0.039 0.183 0.46 8.0 -9999.0 0.0 8.0 PIK3CA 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP -0.088 0.153 -9999.0 0.0 -0.512 4.0 4.0 angiogenesis -0.031 0.17 -9999.0 0.0 -1.034 2.0 2.0 LCK -0.051 0.212 -9999.0 0.0 -1.27 2.0 2.0