E-cadherin signaling in keratinocytes Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations keratinocyte differentiation -0.006 0.172 -9999.0 0.0 -0.479 7.0 7.0 adherens junction organization -0.041 0.195 -9999.0 0.0 -0.511 7.0 7.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.052 0.214 -9999.0 0.0 -0.517 9.0 9.0 FMN1 -0.025 0.166 -9999.0 0.0 -0.427 6.0 6.0 mol:IP3 -0.015 0.166 -9999.0 0.0 -0.464 7.0 7.0 E-cadherin/Ca2+/beta catenin-gamma catenin/alpha catenin/p120 catenin -0.026 0.175 -9999.0 0.0 -0.45 6.0 6.0 CTNNB1 0.021 0.004 -9999.0 0.0 -9999.0 0.0 0.0 AKT1 -0.009 0.171 -9999.0 0.0 -0.493 6.0 6.0 E-cadherin/beta catenin-gamma catenin/alpha catenin/p120 catenin -0.041 0.206 -9999.0 0.0 -0.57 7.0 7.0 CTNND1 -0.021 0.168 -9999.0 0.0 -0.715 4.0 4.0 mol:PI-4-5-P2 -0.013 0.163 -9999.0 0.0 -0.563 3.0 3.0 VASP -0.018 0.168 -9999.0 0.0 -0.581 3.0 3.0 ZYX -0.021 0.169 -9999.0 0.0 -0.581 3.0 3.0 JUB -0.08 0.258 -9999.0 0.0 -0.593 12.0 12.0 EGFR(dimer) -0.079 0.234 -9999.0 0.0 -0.578 9.0 9.0 E-cadherin/beta catenin-gamma catenin -0.07 0.167 -9999.0 0.0 -0.432 10.0 10.0 mol:PI-3-4-5-P3 -0.022 0.179 -9999.0 0.0 -0.502 7.0 7.0 PIK3CA 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PI3K -0.023 0.184 -9999.0 0.0 -0.515 7.0 7.0 FYN -0.099 0.268 -9999.0 0.0 -0.655 11.0 11.0 mol:Ca2+ -0.014 0.162 -9999.0 0.0 -0.452 7.0 7.0 JUP 0.011 0.086 -9999.0 0.0 -0.71 1.0 1.0 PIK3R1 -0.038 0.196 -9999.0 0.0 -0.684 6.0 6.0 mol:DAG -0.015 0.166 -9999.0 0.0 -0.464 7.0 7.0 CDH1 -0.097 0.25 -9999.0 0.0 -0.624 13.0 13.0 RhoA/GDP -0.057 0.216 -9999.0 0.0 -0.517 9.0 9.0 establishment of polarity of embryonic epithelium -0.016 0.164 -9999.0 0.0 -0.563 3.0 3.0 SRC 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAC1 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RHOA 0.01 0.085 -9999.0 0.0 -0.708 1.0 1.0 EGFR -0.106 0.26 -9999.0 0.0 -0.629 14.0 14.0 CASR -0.058 0.187 -9999.0 0.0 -0.523 6.0 6.0 RhoA/GTP -0.058 0.13 -9999.0 0.0 -0.428 6.0 6.0 AKT2 -0.009 0.171 -9999.0 0.0 -0.493 6.0 6.0 actin cable formation -0.017 0.163 -9999.0 0.0 -0.564 3.0 3.0 apoptosis 0.011 0.17 0.47 7.0 -9999.0 0.0 7.0 CTNNA1 0.019 0.006 -9999.0 0.0 -9999.0 0.0 0.0 mol:GDP -0.068 0.23 -9999.0 0.0 -0.571 9.0 9.0 PIP5K1A -0.014 0.167 -9999.0 0.0 -0.581 3.0 3.0 PLCG1 -0.016 0.17 -9999.0 0.0 -0.476 7.0 7.0 Rac1/GTP -0.108 0.187 -9999.0 0.0 -0.628 6.0 6.0 homophilic cell adhesion -0.0 0.005 -9999.0 0.0 -9999.0 0.0 0.0