Arf6 downstream pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations PLAUR 0.039 0.0 -9999.0 0.0 -9999.0 0.0 0.0 regulation of axonogenesis -0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 myoblast fusion -0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 regulation of calcium-dependent cell-cell adhesion -0.037 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF1/GTP 0.022 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:GM1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:Choline 0.014 0.044 -9999.0 0.0 -9999.0 0.0 0.0 lamellipodium assembly 0.024 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.028 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6/GTP/NME1/Tiam1 0.038 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6/GDP 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF1/GDP 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAB11A 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TIAM1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 fibronectin binding 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MAPK1 0.028 0.0 -9999.0 0.0 -9999.0 0.0 0.0 actin filament bundle formation -0.017 0.041 -9999.0 0.0 -9999.0 0.0 0.0 KALRN 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAB11FIP3/RAB11A 0.022 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RhoA/GDP 0.017 0.041 -9999.0 0.0 -9999.0 0.0 0.0 NME1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP 0.028 0.0 -9999.0 0.0 -9999.0 0.0 0.0 substrate adhesion-dependent cell spreading 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cortical actin cytoskeleton organization 0.024 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAC1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 liver development 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6/GTP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RhoA/GTP 0.008 0.051 -9999.0 0.0 -0.189 1.0 1.0 mol:GDP 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARF6/GTP/RAB11FIP3/RAB11A 0.03 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RHOA -0.006 0.081 -9999.0 0.0 -0.321 1.0 1.0 PLD1 0.008 0.051 -9999.0 0.0 -0.19 1.0 1.0 RAB11FIP3 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 tube morphogenesis 0.024 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ruffle organization 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 regulation of epithelial cell migration 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLD2 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PIP5K1A 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 mol:Phosphatidic acid 0.014 0.044 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GTP 0.024 0.0 -9999.0 0.0 -9999.0 0.0 0.0