Circadian rhythm pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations chromatin modification -0.041 0.155 -9999.0 0.0 -0.512 1.0 1.0 CLOCK 0.02 0.002 -9999.0 0.0 -9999.0 0.0 0.0 TIMELESS/CRY2 0.017 0.104 -9999.0 0.0 -9999.0 0.0 0.0 DEC1/BMAL1 -0.021 0.138 -9999.0 0.0 -0.411 3.0 3.0 ATR 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NR1D1 0.04 0.05 -9999.0 0.0 -9999.0 0.0 0.0 ARNTL -0.002 0.116 -9999.0 0.0 -0.591 1.0 1.0 TIMELESS 0.033 0.086 -9999.0 0.0 -0.407 1.0 1.0 NPAS2 0.02 0.002 -9999.0 0.0 -9999.0 0.0 0.0 CRY2 -0.019 0.131 -9999.0 0.0 -0.472 2.0 2.0 mol:CO -0.014 0.014 -9999.0 0.0 -9999.0 0.0 0.0 CHEK1 -0.15 0.242 -9999.0 0.0 -0.483 9.0 9.0 mol:HEME 0.014 0.014 -9999.0 0.0 -9999.0 0.0 0.0 PER1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 BMAL/CLOCK/NPAS2 0.038 0.084 -9999.0 0.0 -0.393 1.0 1.0 BMAL1/CLOCK 0.027 0.128 -9999.0 0.0 -0.558 1.0 1.0 S phase of mitotic cell cycle -0.041 0.155 -9999.0 0.0 -0.512 1.0 1.0 TIMELESS/CHEK1/ATR -0.041 0.157 -9999.0 0.0 -0.52 1.0 1.0 mol:NADPH 0.014 0.014 -9999.0 0.0 -9999.0 0.0 0.0 PER1/TIMELESS 0.037 0.079 -9999.0 0.0 -9999.0 0.0 0.0 PER1-2 / CRY1-2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 DEC1 -0.026 0.153 -9999.0 0.0 -0.566 2.0 2.0