Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.039 0.186 -9999.0 0.0 -0.339 6.0 6.0 MAP3K8 0.007 0.089 -9999.0 0.0 -0.276 2.0 2.0 FOS -0.013 0.125 -9999.0 0.0 -0.448 1.0 1.0 PRKCA 0.024 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.013 0.041 -9999.0 0.0 -0.148 1.0 1.0 HRAS 0.031 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.004 0.007 -9999.0 0.0 -0.014 8.0 8.0 NRAS 0.027 0.014 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.037 0.03 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.01 0.098 -9999.0 0.0 -0.416 1.0 1.0 MAP2K1 0.02 0.067 -9999.0 0.0 -0.198 1.0 1.0 ELK1 0.02 0.028 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.006 0.019 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 8.0 8.0 MAPK1 -0.003 0.111 -9999.0 0.0 -0.345 2.0 2.0 RAF1 0.005 0.021 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.029 0.012 -9999.0 0.0 -9999.0 0.0 0.0