Glypican 1 network Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations GPC1/FGF2 dimer/FGFR1 dimer -0.035 0.111 -9999.0 0.0 -0.501 1.0 1.0 fibroblast growth factor receptor signaling pathway -0.034 0.111 -9999.0 0.0 -0.499 1.0 1.0 LAMA1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PRNP -0.008 0.137 -9999.0 0.0 -0.773 1.0 1.0 GPC1/SLIT2 -0.066 0.179 -9999.0 0.0 -0.532 4.0 4.0 SMAD2 0.007 0.111 -9999.0 0.0 -0.45 1.0 1.0 GPC1/PrPc/Cu2+ -0.042 0.133 -9999.0 0.0 -0.445 3.0 3.0 GPC1/Laminin alpha1 -0.03 0.119 -9999.0 0.0 -0.478 2.0 2.0 TDGF1 -0.001 0.094 -9999.0 0.0 -0.526 1.0 1.0 CRIPTO/GPC1 -0.041 0.133 -9999.0 0.0 -0.442 3.0 3.0 APP/GPC1 -0.078 0.186 -9999.0 0.0 -0.499 5.0 5.0 mol:NO -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 YES1 -0.003 0.121 -9999.0 0.0 -0.5 1.0 1.0 FLT1 -0.008 0.137 -9999.0 0.0 -0.773 1.0 1.0 GPC1/TGFB/TGFBR1/TGFBR2 -0.025 0.1 -9999.0 0.0 -0.501 1.0 1.0 SERPINC1 -0.001 0.094 -9999.0 0.0 -0.526 1.0 1.0 FYN -0.003 0.121 -9999.0 0.0 -0.5 1.0 1.0 FGR -0.003 0.121 -9999.0 0.0 -0.5 1.0 1.0 positive regulation of MAPKKK cascade 0.007 0.125 -9999.0 0.0 -0.481 1.0 1.0 SLIT2 -0.033 0.191 -9999.0 0.0 -0.773 2.0 2.0 GPC1/NRG -0.041 0.133 -9999.0 0.0 -0.442 3.0 3.0 NRG1 -0.001 0.094 -9999.0 0.0 -0.526 1.0 1.0 GPC1/VEGF165 homodimer/VEGFR1 homodimer -0.055 0.191 -9999.0 0.0 -0.731 2.0 2.0 LYN -0.003 0.121 -9999.0 0.0 -0.5 1.0 1.0 mol:Spermine -0.017 0.125 -9999.0 0.0 -0.489 2.0 2.0 cell growth -0.034 0.111 -9999.0 0.0 -0.499 1.0 1.0 BMP signaling pathway 0.025 0.164 0.648 2.0 -9999.0 0.0 2.0 SRC -0.003 0.121 -9999.0 0.0 -0.5 1.0 1.0 TGFBR1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:Cu2+ -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G2A 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 GPC1 -0.025 0.164 -9999.0 0.0 -0.65 2.0 2.0 TGFBR1 (dimer) 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 VEGFA -0.008 0.137 -9999.0 0.0 -0.773 1.0 1.0 BLK -0.03 0.156 -9999.0 0.0 -0.501 2.0 2.0 HCK -0.02 0.149 -9999.0 0.0 -0.501 2.0 2.0 FGF2 -0.001 0.094 -9999.0 0.0 -0.526 1.0 1.0 FGFR1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 VEGFR1 homodimer -0.008 0.137 -9999.0 0.0 -0.772 1.0 1.0 TGFBR2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell death -0.078 0.186 -9999.0 0.0 -0.498 5.0 5.0 ATIII/GPC1 -0.041 0.133 -9999.0 0.0 -0.442 3.0 3.0 PLA2G2A/GPC1 -0.03 0.119 -9999.0 0.0 -0.478 2.0 2.0 LCK -0.02 0.149 -9999.0 0.0 -0.501 2.0 2.0 neuron differentiation -0.041 0.132 -9999.0 0.0 -0.441 3.0 3.0 PrPc/Cu2+ -0.019 0.104 -9999.0 0.0 -0.596 1.0 1.0 APP -0.05 0.209 -9999.0 0.0 -0.691 3.0 3.0 TGFBR2 (dimer) 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0