Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 -0.038 0.173 -9999.0 0.0 -0.556 15.0 15.0 EPHB2 -0.071 0.216 -9999.0 0.0 -0.578 23.0 23.0 EFNB1 -0.042 0.18 -9999.0 0.0 -0.488 21.0 21.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.104 0.209 -9999.0 0.0 -0.551 16.0 16.0 Ephrin B2/EPHB1-2 -0.126 0.202 -9999.0 0.0 -0.461 30.0 30.0 neuron projection morphogenesis -0.131 0.176 -9999.0 0.0 -0.526 16.0 16.0 Ephrin B1/EPHB1-2/Tiam1 -0.12 0.224 -9999.0 0.0 -0.569 18.0 18.0 DNM1 0.004 0.086 -9999.0 0.0 -0.512 4.0 4.0 cell-cell signaling -0.0 0.002 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.061 0.237 -9999.0 0.0 -0.74 16.0 16.0 YES1 -0.1 0.3 -9999.0 0.0 -0.97 16.0 16.0 Ephrin B1/EPHB1-2/NCK2 -0.12 0.224 -9999.0 0.0 -0.45 37.0 37.0 PI3K -0.093 0.273 -9999.0 0.0 -0.78 18.0 18.0 mol:GDP -0.119 0.22 -9999.0 0.0 -0.562 18.0 18.0 ITGA2B 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 endothelial cell proliferation -0.03 0.154 -9999.0 0.0 -0.394 20.0 20.0 FYN -0.101 0.297 -9999.0 0.0 -0.927 17.0 17.0 MAP3K7 -0.07 0.242 -9999.0 0.0 -0.767 16.0 16.0 FGR -0.099 0.292 -9999.0 0.0 -0.949 16.0 16.0 TIAM1 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PIK3R1 -0.038 0.168 -9999.0 0.0 -0.523 16.0 16.0 RGS3 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.078 0.255 -9999.0 0.0 -0.762 16.0 16.0 LYN -0.1 0.297 -9999.0 0.0 -0.927 17.0 17.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.096 0.277 -9999.0 0.0 -0.901 16.0 16.0 Ephrin B1/EPHB1-2 -0.092 0.256 -9999.0 0.0 -0.796 17.0 17.0 SRC -0.098 0.293 -9999.0 0.0 -0.911 17.0 17.0 ITGB3 -0.005 0.107 -9999.0 0.0 -0.488 7.0 7.0 EPHB1 -0.123 0.23 -9999.0 0.0 -0.487 43.0 43.0 EPHB4 -0.013 0.137 -9999.0 0.0 -0.589 8.0 8.0 RAC1 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 -0.03 0.155 -9999.0 0.0 -0.396 20.0 20.0 alphaIIb/beta3 Integrin 0.011 0.078 -9999.0 0.0 -0.339 7.0 7.0 BLK -0.108 0.293 -9999.0 0.0 -0.922 17.0 17.0 HCK -0.107 0.298 -9999.0 0.0 -0.93 17.0 17.0 regulation of stress fiber formation 0.119 0.22 0.445 37.0 -9999.0 0.0 37.0 MAPK8 -0.048 0.226 -9999.0 0.0 -0.695 16.0 16.0 Ephrin B1/EPHB1-2/RGS3 -0.12 0.224 -9999.0 0.0 -0.45 37.0 37.0 endothelial cell migration -0.107 0.262 -9999.0 0.0 -0.707 21.0 21.0 NCK2 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 -0.074 0.253 -9999.0 0.0 -0.737 19.0 19.0 regulation of focal adhesion formation 0.119 0.22 0.445 37.0 -9999.0 0.0 37.0 chemotaxis 0.119 0.22 0.445 37.0 -9999.0 0.0 37.0 PIK3CA -0.003 0.107 -9999.0 0.0 -0.528 6.0 6.0 Rac1/GTP -0.134 0.182 -9999.0 0.0 -0.543 16.0 16.0 angiogenesis -0.091 0.253 -9999.0 0.0 -0.79 17.0 17.0 LCK -0.111 0.301 -9999.0 0.0 -0.94 17.0 17.0