E-cadherin signaling in keratinocytes Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations keratinocyte differentiation -0.013 0.149 -9999.0 0.0 -0.455 10.0 10.0 adherens junction organization -0.025 0.143 -9999.0 0.0 -0.461 8.0 8.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.048 0.185 -9999.0 0.0 -0.538 11.0 11.0 FMN1 -0.018 0.133 -9999.0 0.0 -0.318 21.0 21.0 mol:IP3 -0.016 0.134 -9999.0 0.0 -0.466 7.0 7.0 E-cadherin/Ca2+/beta catenin-gamma catenin/alpha catenin/p120 catenin -0.019 0.139 -9999.0 0.0 -0.333 21.0 21.0 CTNNB1 0.008 0.077 -9999.0 0.0 -0.527 3.0 3.0 AKT1 -0.018 0.157 -9999.0 0.0 -0.512 9.0 9.0 E-cadherin/beta catenin-gamma catenin/alpha catenin/p120 catenin -0.01 0.152 -9999.0 0.0 -0.507 9.0 9.0 CTNND1 -0.005 0.123 -9999.0 0.0 -0.678 5.0 5.0 mol:PI-4-5-P2 -0.008 0.131 -9999.0 0.0 -0.423 7.0 7.0 VASP -0.015 0.146 -9999.0 0.0 -0.462 9.0 9.0 ZYX -0.023 0.15 -9999.0 0.0 -0.454 10.0 10.0 JUB -0.043 0.168 -9999.0 0.0 -0.393 19.0 19.0 EGFR(dimer) -0.065 0.198 -9999.0 0.0 -0.454 23.0 23.0 E-cadherin/beta catenin-gamma catenin -0.026 0.155 -9999.0 0.0 -0.42 18.0 18.0 mol:PI-3-4-5-P3 -0.023 0.146 -9999.0 0.0 -0.449 10.0 10.0 PIK3CA -0.003 0.108 -9999.0 0.0 -0.528 6.0 6.0 PI3K -0.023 0.149 -9999.0 0.0 -0.46 10.0 10.0 FYN -0.001 0.126 -9999.0 0.0 -0.422 5.0 5.0 mol:Ca2+ -0.016 0.132 -9999.0 0.0 -0.454 7.0 7.0 JUP -0.034 0.18 -9999.0 0.0 -0.649 12.0 12.0 PIK3R1 -0.038 0.169 -9999.0 0.0 -0.524 16.0 16.0 mol:DAG -0.016 0.134 -9999.0 0.0 -0.466 7.0 7.0 CDH1 -0.019 0.152 -9999.0 0.0 -0.621 9.0 9.0 RhoA/GDP -0.048 0.185 -9999.0 0.0 -0.538 11.0 11.0 establishment of polarity of embryonic epithelium -0.014 0.143 -9999.0 0.0 -0.451 9.0 9.0 SRC 0.015 0.038 -9999.0 0.0 -0.458 1.0 1.0 RAC1 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RHOA 0.018 0.0 -9999.0 0.0 -9999.0 0.0 0.0 EGFR -0.093 0.24 -9999.0 0.0 -0.593 28.0 28.0 CASR -0.008 0.129 -9999.0 0.0 -0.427 7.0 7.0 RhoA/GTP -0.006 0.122 -9999.0 0.0 -0.431 6.0 6.0 AKT2 -0.018 0.145 -9999.0 0.0 -0.45 9.0 9.0 actin cable formation -0.015 0.142 -9999.0 0.0 -0.449 9.0 9.0 apoptosis 0.018 0.145 0.428 11.0 -9999.0 0.0 11.0 CTNNA1 0.018 0.004 -9999.0 0.0 -9999.0 0.0 0.0 mol:GDP -0.063 0.197 -9999.0 0.0 -0.556 13.0 13.0 PIP5K1A -0.009 0.133 -9999.0 0.0 -0.433 7.0 7.0 PLCG1 -0.017 0.137 -9999.0 0.0 -0.478 7.0 7.0 Rac1/GTP -0.09 0.159 -9999.0 0.0 -0.509 13.0 13.0 homophilic cell adhesion -0.0 0.004 -9999.0 0.0 -9999.0 0.0 0.0