ceramide signaling pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations MAP4K4 -0.012 0.112 -9999.0 0.0 -0.207 118.0 118.0 BAG4 0.022 0.012 -9999.0 0.0 -0.122 4.0 4.0 BAD 0.007 0.036 -9999.0 0.0 -0.113 20.0 20.0 NFKBIA 0.016 0.028 -9999.0 0.0 -0.122 21.0 21.0 BIRC3 -0.005 0.053 -9999.0 0.0 -0.122 94.0 94.0 BAX 0.007 0.036 -9999.0 0.0 -0.114 19.0 19.0 EnzymeConsortium:3.1.4.12 0.0 0.027 -9999.0 0.0 -0.063 41.0 41.0 IKBKB -0.009 0.107 -9999.0 0.0 -0.195 119.0 119.0 MAP2K2 0.013 0.036 -9999.0 0.0 -0.101 25.0 25.0 MAP2K1 0.015 0.033 -9999.0 0.0 -0.099 20.0 20.0 SMPD1 0.005 0.028 -9999.0 0.0 -0.094 16.0 16.0 GO:0005551 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 FADD/Caspase 8 -0.005 0.116 -9999.0 0.0 -0.202 119.0 119.0 MAP2K4 0.008 0.039 -9999.0 0.0 -0.105 33.0 33.0 protein ubiquitination -0.012 0.109 -9999.0 0.0 -0.246 59.0 59.0 EnzymeConsortium:2.7.1.37 0.017 0.034 -9999.0 0.0 -0.112 12.0 12.0 response to UV 0.0 0.0 -9999.0 0.0 -0.001 8.0 8.0 RAF1 0.011 0.035 -9999.0 0.0 -0.103 24.0 24.0 CRADD 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 mol:ceramide 0.003 0.038 -9999.0 0.0 -0.113 23.0 23.0 I-kappa-B-alpha/RELA/p50/ubiquitin 0.018 0.041 -9999.0 0.0 -0.097 61.0 61.0 MADD 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 MAP3K1 0.004 0.04 -9999.0 0.0 -0.117 30.0 30.0 TRADD 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 RELA/p50 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 MAPK3 0.017 0.035 -9999.0 0.0 -0.121 11.0 11.0 MAPK1 0.016 0.037 -9999.0 0.0 -0.117 16.0 16.0 p50/RELA/I-kappa-B-alpha 0.018 0.049 -9999.0 0.0 -0.119 61.0 61.0 FADD -0.01 0.112 -9999.0 0.0 -0.205 118.0 118.0 KSR1 0.008 0.036 -9999.0 0.0 -0.112 20.0 20.0 MAPK8 0.008 0.042 -9999.0 0.0 -0.11 37.0 37.0 TRAF2 0.024 0.001 -9999.0 0.0 -9999.0 0.0 0.0 response to radiation 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CHUK -0.013 0.11 -9999.0 0.0 -0.202 119.0 119.0 TNF R/SODD 0.027 0.034 -9999.0 0.0 -0.141 18.0 18.0 TNF 0.02 0.02 -9999.0 0.0 -0.122 11.0 11.0 CYCS 0.006 0.038 0.097 1.0 -0.114 22.0 23.0 IKBKG -0.009 0.107 -9999.0 0.0 -0.193 119.0 119.0 TNF/TNF R/TRADD/MADD/cIAP/RIP/TRAF2/RAIDD -0.014 0.116 -9999.0 0.0 -0.218 118.0 118.0 RELA 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 RIPK1 0.022 0.011 -9999.0 0.0 -0.122 3.0 3.0 AIFM1 0.001 0.044 0.097 1.0 -0.124 33.0 34.0 TNF/TNF R/SODD 0.038 0.034 -9999.0 0.0 -0.109 20.0 20.0 TNFRSF1A 0.021 0.016 -9999.0 0.0 -0.122 7.0 7.0 response to heat 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CASP8 0.005 0.126 -9999.0 0.0 -0.667 17.0 17.0 NSMAF -0.011 0.113 -9999.0 0.0 -0.206 118.0 118.0 response to hydrogen peroxide 0.0 0.0 -9999.0 0.0 -0.001 8.0 8.0 BCL2 0.016 0.031 -9999.0 0.0 -0.122 27.0 27.0