Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.023 0.042 0.112 47.0 -9999.0 0.0 47.0 KIRREL 0.018 0.028 -9999.0 0.0 -0.123 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.023 0.043 -9999.0 0.0 -0.112 47.0 47.0 PLCG1 0.019 0.024 -9999.0 0.0 -0.122 16.0 16.0 ARRB2 0.022 0.014 -9999.0 0.0 -0.122 5.0 5.0 WASL 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 Nephrin/NEPH1/podocin/CD2AP 0.036 0.056 -9999.0 0.0 -0.108 64.0 64.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.021 0.053 -9999.0 0.0 -0.142 34.0 34.0 FYN 0.014 0.034 -9999.0 0.0 -0.112 26.0 26.0 mol:Ca2+ 0.041 0.047 -9999.0 0.0 -0.109 38.0 38.0 mol:DAG 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 NPHS2 0.022 0.014 -9999.0 0.0 -0.082 7.0 7.0 mol:IP3 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 regulation of endocytosis 0.031 0.045 -9999.0 0.0 -0.1 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol 0.034 0.035 -9999.0 0.0 -0.1 27.0 27.0 establishment of cell polarity 0.023 0.042 -9999.0 0.0 -0.112 47.0 47.0 Nephrin/NEPH1/podocin/NCK1-2 0.049 0.054 -9999.0 0.0 -0.095 56.0 56.0 Nephrin/NEPH1/beta Arrestin2 0.033 0.046 -9999.0 0.0 -0.101 29.0 29.0 NPHS1 0.021 0.02 -9999.0 0.0 -0.128 9.0 9.0 Nephrin/NEPH1/podocin 0.025 0.045 -9999.0 0.0 -0.111 28.0 28.0 TJP1 0.021 0.01 -9999.0 0.0 -0.122 2.0 2.0 NCK1 0.02 0.019 -9999.0 0.0 -0.122 9.0 9.0 NCK2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.043 0.048 -9999.0 0.0 -0.109 38.0 38.0 CD2AP 0.02 0.017 -9999.0 0.0 -0.122 7.0 7.0 Nephrin/NEPH1/podocin/GRB2 0.047 0.042 -9999.0 0.0 -0.11 28.0 28.0 GRB2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.019 0.029 -9999.0 0.0 -0.087 27.0 27.0 cytoskeleton organization 0.022 0.047 -9999.0 0.0 -0.132 30.0 30.0 Nephrin/NEPH1 0.022 0.029 -9999.0 0.0 -0.072 47.0 47.0 Nephrin/NEPH1/ZO-1 0.027 0.055 -9999.0 0.0 -0.128 55.0 55.0