Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 -0.014 0.099 -9999.0 0.0 -0.322 5.0 5.0 EPHB2 -0.019 0.107 -9999.0 0.0 -0.319 6.0 6.0 EFNB1 -0.033 0.116 -9999.0 0.0 -0.26 11.0 11.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.031 0.116 -9999.0 0.0 -0.277 5.0 5.0 Ephrin B2/EPHB1-2 -0.027 0.121 -9999.0 0.0 -0.289 7.0 7.0 neuron projection morphogenesis -0.046 0.099 -9999.0 0.0 -0.266 5.0 5.0 Ephrin B1/EPHB1-2/Tiam1 -0.04 0.123 -9999.0 0.0 -0.301 5.0 5.0 DNM1 0.01 0.058 -9999.0 0.0 -0.412 1.0 1.0 cell-cell signaling 0.001 0.003 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 -0.141 0.245 -9999.0 0.0 -0.531 15.0 15.0 YES1 -0.213 0.348 -9999.0 0.0 -0.769 15.0 15.0 Ephrin B1/EPHB1-2/NCK2 -0.036 0.116 -9999.0 0.0 -0.286 4.0 4.0 PI3K -0.167 0.25 -9999.0 0.0 -0.535 16.0 16.0 mol:GDP -0.04 0.121 -9999.0 0.0 -0.299 5.0 5.0 ITGA2B 0.012 0.043 -9999.0 0.0 -0.3 1.0 1.0 endothelial cell proliferation 0.001 0.067 -9999.0 0.0 -0.184 6.0 6.0 FYN -0.221 0.351 -9999.0 0.0 -0.778 15.0 15.0 MAP3K7 -0.156 0.259 -9999.0 0.0 -0.568 15.0 15.0 FGR -0.21 0.343 -9999.0 0.0 -0.758 15.0 15.0 TIAM1 0.01 0.058 -9999.0 0.0 -0.411 1.0 1.0 PIK3R1 -0.038 0.134 -9999.0 0.0 -0.355 8.0 8.0 RGS3 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.164 0.233 -9999.0 0.0 -0.488 17.0 17.0 LYN -0.214 0.347 -9999.0 0.0 -0.769 15.0 15.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.204 0.317 -9999.0 0.0 -0.711 15.0 15.0 Ephrin B1/EPHB1-2 -0.18 0.275 -9999.0 0.0 -0.619 15.0 15.0 SRC -0.21 0.343 -9999.0 0.0 -0.758 15.0 15.0 ITGB3 -0.026 0.113 -9999.0 0.0 -0.315 7.0 7.0 EPHB1 -0.037 0.125 -9999.0 0.0 -0.314 9.0 9.0 EPHB4 0.01 0.058 -9999.0 0.0 -0.411 1.0 1.0 RAC1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 0.001 0.067 -9999.0 0.0 -0.185 6.0 6.0 alphaIIb/beta3 Integrin -0.008 0.09 -9999.0 0.0 -0.232 7.0 7.0 BLK -0.214 0.343 -9999.0 0.0 -0.761 15.0 15.0 HCK -0.22 0.347 -9999.0 0.0 -0.772 15.0 15.0 regulation of stress fiber formation 0.037 0.114 0.284 4.0 -9999.0 0.0 4.0 MAPK8 -0.136 0.232 -9999.0 0.0 -0.5 15.0 15.0 Ephrin B1/EPHB1-2/RGS3 -0.036 0.116 -9999.0 0.0 -0.286 4.0 4.0 endothelial cell migration -0.141 0.23 -9999.0 0.0 -0.477 16.0 16.0 NCK2 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 -0.157 0.243 -9999.0 0.0 -0.478 19.0 19.0 regulation of focal adhesion formation 0.037 0.114 0.284 4.0 -9999.0 0.0 4.0 chemotaxis 0.037 0.114 0.284 4.0 -9999.0 0.0 4.0 PIK3CA 0.01 0.058 -9999.0 0.0 -0.411 1.0 1.0 Rac1/GTP -0.034 0.11 -9999.0 0.0 -0.271 5.0 5.0 angiogenesis -0.179 0.273 -9999.0 0.0 -0.615 15.0 15.0 LCK -0.219 0.344 -9999.0 0.0 -0.765 15.0 15.0