Glypican 1 network Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations GPC1/FGF2 dimer/FGFR1 dimer -0.017 0.107 -9999.0 0.0 -0.246 8.0 8.0 fibroblast growth factor receptor signaling pathway -0.017 0.106 -9999.0 0.0 -0.245 8.0 8.0 LAMA1 -0.034 0.124 -9999.0 0.0 -0.327 8.0 8.0 PRNP 0.012 0.043 -9999.0 0.0 -0.3 1.0 1.0 GPC1/SLIT2 -0.089 0.156 -9999.0 0.0 -0.271 21.0 21.0 SMAD2 0.012 0.067 -9999.0 0.0 -0.197 5.0 5.0 GPC1/PrPc/Cu2+ -0.004 0.078 -9999.0 0.0 -0.222 6.0 6.0 GPC1/Laminin alpha1 -0.035 0.139 -9999.0 0.0 -0.305 10.0 10.0 TDGF1 -0.089 0.174 -9999.0 0.0 -0.366 15.0 15.0 CRIPTO/GPC1 -0.077 0.146 -9999.0 0.0 -0.266 19.0 19.0 APP/GPC1 -0.002 0.089 -9999.0 0.0 -0.28 5.0 5.0 mol:NO -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 YES1 -0.057 0.122 -9999.0 0.0 -0.243 13.0 13.0 FLT1 -0.014 0.112 -9999.0 0.0 -0.411 4.0 4.0 GPC1/TGFB/TGFBR1/TGFBR2 0.011 0.076 -9999.0 0.0 -0.227 5.0 5.0 SERPINC1 0.012 0.043 -9999.0 0.0 -0.3 1.0 1.0 FYN -0.07 0.146 -9999.0 0.0 -0.273 14.0 14.0 FGR -0.057 0.122 -9999.0 0.0 -0.243 13.0 13.0 positive regulation of MAPKKK cascade -0.079 0.155 -9999.0 0.0 -0.3 14.0 14.0 SLIT2 -0.109 0.181 -9999.0 0.0 -0.361 18.0 18.0 GPC1/NRG -0.002 0.089 -9999.0 0.0 -0.28 5.0 5.0 NRG1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 GPC1/VEGF165 homodimer/VEGFR1 homodimer -0.021 0.125 -9999.0 0.0 -0.272 10.0 10.0 LYN -0.06 0.127 -9999.0 0.0 -0.248 14.0 14.0 mol:Spermine -0.016 0.087 -9999.0 0.0 -0.288 5.0 5.0 cell growth -0.017 0.106 -9999.0 0.0 -0.245 8.0 8.0 BMP signaling pathway 0.022 0.124 0.41 5.0 -9999.0 0.0 5.0 SRC -0.057 0.122 -9999.0 0.0 -0.243 13.0 13.0 TGFBR1 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:Cu2+ 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G2A -0.016 0.106 -9999.0 0.0 -0.344 5.0 5.0 GPC1 -0.022 0.124 -9999.0 0.0 -0.411 5.0 5.0 TGFBR1 (dimer) 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 VEGFA -0.006 0.098 -9999.0 0.0 -0.411 3.0 3.0 BLK -0.065 0.124 -9999.0 0.0 -0.242 14.0 14.0 HCK -0.078 0.126 -9999.0 0.0 -0.24 16.0 16.0 FGF2 0.006 0.06 -9999.0 0.0 -0.3 2.0 2.0 FGFR1 -0.018 0.112 -9999.0 0.0 -0.366 5.0 5.0 VEGFR1 homodimer -0.014 0.112 -9999.0 0.0 -0.41 4.0 4.0 TGFBR2 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell death -0.002 0.089 -9999.0 0.0 -0.279 5.0 5.0 ATIII/GPC1 -0.006 0.101 -9999.0 0.0 -0.315 5.0 5.0 PLA2G2A/GPC1 -0.026 0.11 -9999.0 0.0 -0.254 10.0 10.0 LCK -0.079 0.128 -9999.0 0.0 -0.246 16.0 16.0 neuron differentiation -0.002 0.089 -9999.0 0.0 -0.279 5.0 5.0 PrPc/Cu2+ 0.009 0.029 -9999.0 0.0 -0.203 1.0 1.0 APP 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TGFBR2 (dimer) 0.017 0.0 -9999.0 0.0 -9999.0 0.0 0.0