| MutSigPreprocess1 individual_set_id | BRCA |
| MutSigPreprocess1 maf2 | dependentsValues3473175210602024128.tsv |
| MutSigPreprocess1 maflabel1 | Broad |
| MutSigPreprocess1 maflabel2 | WashU |
| MutSigPreprocess1 maflabel3 | Baylor |
| MutSigPreprocess1 wig2 | dependentsValues714983547793450256.tsv |
| MutSigPreprocess1 build | hg18 |
| MutSigPreprocess1 context65_dir | /xchip/cga1/lawrence/db/context65 |
| MutSigPreprocess1 context65_wig | /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig |
| MutSigPreprocess1 num_categories | 4 |
| MutSigPreprocess1 target_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt |
| MutSigPreprocess1 paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 individual_set_id | BRCA |
| MutSigRun3 gene_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt |
| MutSigRun3 build | hg18 |
| MutSigRun3 geneset_file | /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt |
| MutSigRun3 cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| MutSigRun3 refseq_file | /xchip/cga1/annotation/db/ucsc/hg18/R.mat |
| MutSigRun3 genome_dir | /xchip/cga1/annotation/db/ucsc/hg18 |
| MutSigRun3 param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 jobcount | 200 |
| GDAC_MutSig_Report4 ind_set | BRCA |
| Execution Times: | |
| Submitted: | 23:45:40 05-12-11 |
| Completed: | |
| Elapsed: | 05 hrs 59 mins 17 secs |
step 1. MutSigPreprocess [id: 48826] preprocess patient list and mutations
urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:63
| individual_set_id | BRCA |
| maf1 | |
| maf2 | dependentsValues3473175210602024128.tsv |
| maf3 | |
| maf4 | |
| maflabel1 | Broad |
| maflabel2 | WashU |
| maflabel3 | Baylor |
| maflabel4 | |
| wig1 | |
| wig2 | dependentsValues714983547793450256.tsv |
| wig3 | |
| wig4 | |
| build | hg18 |
| context65_dir | /xchip/cga1/lawrence/db/context65 |
| context65_wig | /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig |
| num_categories | 4 |
| target_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt |
| paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| Output Files: | |
| BRCA.mutation_preprocessing_report.txt | |
| BRCA.maf | |
| BRCA.patients.txt | |
| BRCA.coverage.prepare.txt | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 23:45:40 05-12-11 |
| Completed: | 23:49:36 05-12-11 |
| Elapsed: | 00 hrs 03 mins 55 secs |
step 2. ProcessCoverageForMutSig [id: 48827] processes coverage from wiggle files and does automatic category discovery
urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:50
| coverage_prepare_file | BRCA.coverage.prepare.txt |
| patient_list | BRCA.patients.txt |
| mutation_list | BRCA.maf |
| Execution Times: | |
| Submitted: | 23:45:40 05-12-11 |
| Completed: | 00:53:39 06-12-11 |
| Elapsed: | 01 hrs 07 mins 58 secs |
step 3. MutSigRun [id: 48828] perform MutSig calculations, generates output tables and report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:120
| individual_set_id | BRCA |
| mutation_file | BRCA.maf |
| coverage_file | BRCA.coverage.mat |
| patient_file | BRCA.patients.txt |
| category_file | BRCA.mutcategs.txt |
| gene_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt |
| build | hg18 |
| geneset_file | /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt |
| cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| refseq_file | /xchip/cga1/annotation/db/ucsc/hg18/R.mat |
| genome_dir | /xchip/cga1/annotation/db/ucsc/hg18 |
| param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| mutation_preprocessing_report_file | BRCA.mutation_preprocessing_report.txt |
| jobcount | 200 |
| Execution Times: | |
| Submitted: | 23:45:40 05-12-11 |
| Completed: | 05:44:26 06-12-11 |
| Elapsed: | 05 hrs 58 mins 45 secs |
step 4. GDAC_MutSig_Report [id: 48829] Somatic Mutation Report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:10
| bar_plot | BRCA.bargraphs.png |
| breakdown_table | BRCA.mutation_breakdown.txt |
| categories_table | BRCA.mutation_rates.txt |
| coverage png | BRCA.covplot.png |
| sig_table | BRCA.sig_genes.txt |
| cosmic_table | BRCA.cosmic_sig_genes.txt |
| cosmic_table2 | BRCA.cosmic_sig_genes2.txt |
| cosmic_muts_table | BRCA.cosmic_mutations.txt |
| cluster_table | BRCA.clustered_muts.txt |
| geneset_table | BRCA.sig_genesets.txt |
| genset_table2 | BRCA.sig_genesets_2.txt |
| patients_c_and_r | BRCA.patients.counts_and_rates.txt |
| ind_set | BRCA |
| mutsig_version | BRCA.MutSig_version.txt |
| Output Files: | |
| report_standalone.html | |
| report.html | |
| report.RData | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 23:45:40 05-12-11 |
| Completed: | 05:44:56 06-12-11 |
| Elapsed: | 05 hrs 59 mins 15 secs |
