MutSigWithNozzleReport Execution Log 7:57 PM Sun May 27, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id UCEC
MutSigPreprocess1 maf2 dependentsValues442964176080433094.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig2 dependentsValues3339408762365244588.tsv
MutSigPreprocess1 build hg18
MutSigPreprocess1 context65_dir /xchip/cga1/lawrence/db/context65
MutSigPreprocess1 context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 individual_set_id UCEC
MutSigRun3 gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
MutSigRun3 build hg18
MutSigRun3 geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg18
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 jobcount 200
GDAC_MutSig_Report4 ind_set UCEC
Execution Times:
Submitted: 19:57:51 27-05-12
Completed:
Elapsed: 10 hrs 33 mins 13 secs

step 1. MutSigPreprocess [id: 104485] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:63
individual_set_id UCEC
maf1
maf2 dependentsValues442964176080433094.tsv
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1
wig2 dependentsValues3339408762365244588.tsv
wig3
wig4
build hg18
context65_dir /xchip/cga1/lawrence/db/context65
context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
num_categories 4
target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
Output Files:
 UCEC.mutation_preprocessing_report.txt
 UCEC.maf
 UCEC.patients.txt
 UCEC.coverage.prepare.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 19:57:51 27-05-12
Completed: 23:46:57 27-05-12
Elapsed: 03 hrs 49 mins 05 secs

step 2. ProcessCoverageForMutSig [id: 104486] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:50
coverage_prepare_file UCEC.coverage.prepare.txt
patient_list UCEC.patients.txt
mutation_list UCEC.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 UCEC.covfiles
 UCEC.summed_coverage.fwi
 UCEC.summed_coverage.fwb
 UCEC.mutcategs.txt
 UCEC.mutcateg_discovery.txt
 UCEC.coverage.mat
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 19:57:51 27-05-12
Completed: 00:08:13 28-05-12
Elapsed: 04 hrs 10 mins 21 secs

step 3. MutSigRun [id: 104487] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:120
individual_set_id UCEC
mutation_file UCEC.maf
coverage_file UCEC.coverage.mat
patient_file UCEC.patients.txt
category_file UCEC.mutcategs.txt
gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
build hg18
geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg18
param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
mutation_preprocessing_report_file UCEC.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 UCEC.MutSig_version.txt
 UCEC.mutation_filtering_report.txt
 UCEC.per_exon.coverage.txt
 UCEC.covplot.png
 UCEC.covplot_hires.png
 UCEC.patients.counts_and_rates.txt
 UCEC.bargraphs.png
 UCEC.num_patients.txt
 UCEC.bargraphs_hires.png
 UCEC.final_analysis_set.maf
 UCEC.mutcategs.txt
 UCEC.per_gene.coverage.txt
 UCEC.per_gene.mutation_counts.txt
 UCEC.mutation_breakdown.txt
 UCEC.mutation_rates.txt
 UCEC.sample_sig_gene_table.txt
 UCEC.sig_genes.txt
 UCEC.sig_genesets.txt
 UCEC.sig_genesets_2.txt
 UCEC.cosmic_sig_genes2.txt
 UCEC.cosmic_mutations.txt
 UCEC.cosmic_mutations.txt_verbose.txt
 UCEC.cosmic_sig_genes.txt
 UCEC.clustered_muts.txt
 UCEC.gene_gene_correlations.txt
 UCEC.power_per_gene.total_coverage.txt
 UCEC.power_per_gene.total_coverage_histogram
 UCEC.power_per_gene.power_stats.txt
 UCEC.power_per_gene.power_stats_full.txt
 UCEC.power_per_gene.power_summary.txt
 UCEC.gene_coverage_plots
 sig_genes.txt
 GGC_full.html
 patients.counts_and_rates.html
 CSG2_full.html
 CSG_full.html
 SG_full.html
 CLM_full.html
 CM_full.html
 report.html
 SGS_full.html
 SGS2_full.html
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 19:57:51 27-05-12
Completed: 06:30:31 28-05-12
Elapsed: 10 hrs 32 mins 40 secs

step 4. GDAC_MutSig_Report [id: 104488] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:10
bar_plot UCEC.bargraphs.png
breakdown_table UCEC.mutation_breakdown.txt
categories_table UCEC.mutation_rates.txt
coverage png UCEC.covplot.png
sig_table UCEC.sig_genes.txt
cosmic_table UCEC.cosmic_sig_genes.txt
cosmic_table2 UCEC.cosmic_sig_genes2.txt
cosmic_muts_table UCEC.cosmic_mutations.txt
cluster_table UCEC.clustered_muts.txt
geneset_table UCEC.sig_genesets.txt
genset_table2 UCEC.sig_genesets_2.txt
patients_c_and_r UCEC.patients.counts_and_rates.txt
ind_set UCEC
mutsig_version UCEC.MutSig_version.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 19:57:51 27-05-12
Completed: 06:31:02 28-05-12
Elapsed: 10 hrs 33 mins 10 secs