Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.035 0.177 -9999.0 0.0 -0.89 1.0 1.0 MAP3K8 0.016 0.116 -9999.0 0.0 -0.63 1.0 1.0 FOS 0.032 0.108 -9999.0 0.0 -0.526 1.0 1.0 PRKCA 0.007 0.127 -9999.0 0.0 -0.444 2.0 2.0 PTPN7 0.033 0.016 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.035 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.0 0.004 -9999.0 0.0 -0.009 5.0 5.0 NRAS 0.02 0.068 -9999.0 0.0 -0.243 2.0 2.0 RAS family/GTP 0.038 0.06 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.037 0.056 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 0.001 0.119 -9999.0 0.0 -0.593 1.0 1.0 ELK1 0.037 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.002 0.099 -9999.0 0.0 -0.532 1.0 1.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.003 5.0 5.0 MAPK1 0.037 0.056 -9999.0 0.0 -9999.0 0.0 0.0 RAF1 0.001 0.098 -9999.0 0.0 -0.532 1.0 1.0 KRAS 0.015 0.068 -9999.0 0.0 -0.244 2.0 2.0