Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.023 0.042 0.112 47.0 -9999.0 0.0 47.0 KIRREL 0.018 0.028 -9999.0 0.0 -0.123 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.023 0.043 -9999.0 0.0 -0.112 47.0 47.0 PLCG1 0.019 0.024 -9999.0 0.0 -0.122 16.0 16.0 ARRB2 0.022 0.014 -9999.0 0.0 -0.122 5.0 5.0 WASL 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 Nephrin/NEPH1/podocin/CD2AP 0.036 0.056 -9999.0 0.0 -0.108 64.0 64.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.021 0.053 -9999.0 0.0 -0.134 53.0 53.0 FYN 0.014 0.034 -9999.0 0.0 -0.112 26.0 26.0 mol:Ca2+ 0.041 0.047 -9999.0 0.0 -0.109 38.0 38.0 mol:DAG 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 NPHS2 0.022 0.014 -9999.0 0.0 -0.122 4.0 4.0 mol:IP3 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 regulation of endocytosis 0.031 0.045 -9999.0 0.0 -0.097 33.0 33.0 Nephrin/NEPH1/podocin/Cholesterol 0.034 0.035 -9999.0 0.0 -0.098 28.0 28.0 establishment of cell polarity 0.023 0.042 -9999.0 0.0 -0.112 47.0 47.0 Nephrin/NEPH1/podocin/NCK1-2 0.049 0.054 -9999.0 0.0 -0.095 55.0 55.0 Nephrin/NEPH1/beta Arrestin2 0.033 0.046 -9999.0 0.0 -0.098 33.0 33.0 NPHS1 0.021 0.02 -9999.0 0.0 -0.103 12.0 12.0 Nephrin/NEPH1/podocin 0.025 0.045 -9999.0 0.0 -0.111 28.0 28.0 TJP1 0.021 0.01 -9999.0 0.0 -0.122 2.0 2.0 NCK1 0.02 0.019 -9999.0 0.0 -0.122 9.0 9.0 NCK2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.043 0.048 -9999.0 0.0 -0.109 38.0 38.0 CD2AP 0.02 0.017 -9999.0 0.0 -0.122 7.0 7.0 Nephrin/NEPH1/podocin/GRB2 0.047 0.042 -9999.0 0.0 -0.11 28.0 28.0 GRB2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.019 0.029 -9999.0 0.0 -0.086 28.0 28.0 cytoskeleton organization 0.022 0.047 -9999.0 0.0 -0.132 30.0 30.0 Nephrin/NEPH1 0.022 0.029 -9999.0 0.0 -0.072 47.0 47.0 Nephrin/NEPH1/ZO-1 0.027 0.055 -9999.0 0.0 -0.128 55.0 55.0