Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.023 0.042 0.142 28.0 -9999.0 0.0 28.0 KIRREL 0.018 0.028 -9999.0 0.0 -0.123 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.023 0.043 -9999.0 0.0 -0.142 28.0 28.0 PLCG1 0.019 0.024 -9999.0 0.0 -0.122 16.0 16.0 ARRB2 0.022 0.014 -9999.0 0.0 -0.122 5.0 5.0 WASL 0.023 0.009 -9999.0 0.0 -0.122 2.0 2.0 Nephrin/NEPH1/podocin/CD2AP 0.036 0.056 -9999.0 0.0 -0.108 64.0 64.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.021 0.053 -9999.0 0.0 -0.142 34.0 34.0 FYN 0.014 0.034 -9999.0 0.0 -0.112 26.0 26.0 mol:Ca2+ 0.041 0.047 -9999.0 0.0 -0.109 38.0 38.0 mol:DAG 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 NPHS2 0.022 0.014 -9999.0 0.0 -0.082 7.0 7.0 mol:IP3 0.042 0.048 -9999.0 0.0 -0.109 38.0 38.0 regulation of endocytosis 0.031 0.045 -9999.0 0.0 -0.098 32.0 32.0 Nephrin/NEPH1/podocin/Cholesterol 0.034 0.035 -9999.0 0.0 -0.1 27.0 27.0 establishment of cell polarity 0.023 0.042 -9999.0 0.0 -0.142 28.0 28.0 Nephrin/NEPH1/podocin/NCK1-2 0.049 0.054 -9999.0 0.0 -0.103 39.0 39.0 Nephrin/NEPH1/beta Arrestin2 0.033 0.046 -9999.0 0.0 -0.099 32.0 32.0 NPHS1 0.021 0.02 -9999.0 0.0 -0.103 12.0 12.0 Nephrin/NEPH1/podocin 0.025 0.045 -9999.0 0.0 -0.111 28.0 28.0 TJP1 0.021 0.01 -9999.0 0.0 -0.122 2.0 2.0 NCK1 0.02 0.019 -9999.0 0.0 -0.122 9.0 9.0 NCK2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.043 0.048 -9999.0 0.0 -0.109 38.0 38.0 CD2AP 0.02 0.017 -9999.0 0.0 -0.122 7.0 7.0 Nephrin/NEPH1/podocin/GRB2 0.047 0.042 -9999.0 0.0 -0.11 28.0 28.0 GRB2 0.023 0.006 -9999.0 0.0 -0.122 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.019 0.029 -9999.0 0.0 -0.089 25.0 25.0 cytoskeleton organization 0.022 0.047 -9999.0 0.0 -0.132 30.0 30.0 Nephrin/NEPH1 0.022 0.029 -9999.0 0.0 -0.091 28.0 28.0 Nephrin/NEPH1/ZO-1 0.027 0.055 -9999.0 0.0 -0.128 55.0 55.0