MutSigWithNozzleReport Execution Log 1:51 PM Sun Aug 5, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id BLCA
MutSigPreprocess1 maf1 dependentsValues6084850074234073497.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 dependentsValues8623850524278887441.tsv
MutSigPreprocess1 build hg19
MutSigPreprocess1 context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
MutSigPreprocess1 context65_wig no_longer_needed
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id BLCA
MutSigRun3 gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
MutSigRun3 build hg19
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId BLCA
GDAC_MutSig_Report5 ind_set BLCA
Execution Times:
Submitted: 13:51:29 05-08-12
Completed:
Elapsed: 04 hrs 47 mins 58 secs

step 1. MutSigPreprocess [id: 142804] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:84
individual_set_id BLCA
maf1 dependentsValues6084850074234073497.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 dependentsValues8623850524278887441.tsv
wig2
wig3
wig4
build hg19
context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
context65_wig no_longer_needed
num_categories 4
target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 BLCA.mutation_preprocessing_report.txt
 BLCA.maf
 BLCA.coverage.prepare.txt
 BLCA.patients.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:51:29 05-08-12
Completed: 13:52:40 05-08-12
Elapsed: 00 hrs 01 mins 10 secs

step 2. ProcessCoverageForMutSig [id: 142805] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:72
coverage_prepare_file BLCA.coverage.prepare.txt
patient_list BLCA.patients.txt
mutation_list BLCA.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 BLCA.summed_coverage.fwi
 BLCA.summed_coverage.fwb
 BLCA.mutcateg_discovery.txt
 BLCA.mutcategs.txt
 BLCA.coverage.mat
 BLCA.covfiles
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 13:51:29 05-08-12
Completed: 14:05:34 05-08-12
Elapsed: 00 hrs 14 mins 04 secs

step 3. MutSigRun [id: 142806] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:153
individual_set_id BLCA
mutation_file BLCA.maf
coverage_file BLCA.coverage.mat
patient_file BLCA.patients.txt
category_file BLCA.mutcategs.txt
gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
build hg19
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg19
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file BLCA.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 BLCA.MutSig_version.txt
 BLCA.mutation_filtering_report.txt
 BLCA.per_exon.coverage.txt
 BLCA.covplot.png
 BLCA.covplot_hires.png
 BLCA.patients.counts_and_rates.txt
 BLCA.bargraphs.png
 BLCA.bargraphs_hires.png
 BLCA.num_patients.txt
 BLCA.final_analysis_set.maf
 BLCA.mutcategs.txt
 BLCA.per_gene.coverage.txt
 BLCA.per_gene.mutation_counts.txt
 BLCA.mutation_breakdown.txt
 BLCA.mutsig2.images
 BLCA.sample_sig_gene_table.txt
 BLCA.mutation_rates.txt
 BLCA.sig_genes.txt
 BLCA.sig_genesets.txt
 BLCA.sig_genesets_2.txt
 BLCA.cosmic_sig_genes2.txt
 BLCA.cosmic_sig_genes.txt
 BLCA.cosmic_mutations.txt_verbose.txt
 BLCA.cosmic_mutations.txt
 BLCA.clustered_muts.txt
 BLCA.gene_gene_correlations.txt
 BLCA.power_per_gene.total_coverage.txt
 BLCA.power_per_gene.total_coverage_histogram
 BLCA.power_per_gene.power_stats.txt
 BLCA.power_per_gene.power_stats_full.txt
 BLCA.power_per_gene.power_summary.txt
 BLCA.gene_coverage_plots
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 13:51:29 05-08-12
Completed: 18:38:39 05-08-12
Elapsed: 04 hrs 47 mins 09 secs

step 4. CoMut [id: 142807]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:4
individualSetId BLCA
patientCRFile BLCA.patients.counts_and_rates.txt
mafFile BLCA.final_analysis_set.maf
mutcategsFile BLCA.mutcategs.txt
sigGenesFile BLCA.sig_genes.txt
Output Files:
 BLCA_coMut.pdf
 BLCA_coMut.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:51:29 05-08-12
Completed: 18:39:09 05-08-12
Elapsed: 04 hrs 47 mins 39 secs

step 5. GDAC_MutSig_Report [id: 142808] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:13
bar_plot BLCA.bargraphs.png
breakdown_table BLCA.mutation_breakdown.txt
categories_table BLCA.mutation_rates.txt
coverage png BLCA.covplot.png
sig_table BLCA.sig_genes.txt
cosmic_table BLCA.cosmic_sig_genes.txt
cosmic_table2 BLCA.cosmic_sig_genes2.txt
cosmic_muts_table BLCA.cosmic_mutations.txt
cluster_table BLCA.clustered_muts.txt
geneset_table BLCA.sig_genesets.txt
genset_table2 BLCA.sig_genesets_2.txt
patients_c_and_r BLCA.patients.counts_and_rates.txt
ind_set BLCA
mutsig_version BLCA.MutSig_version.txt
coMut_plot_png BLCA_coMut.png
coMut_plot_pdf BLCA_coMut.pdf
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:51:29 05-08-12
Completed: 18:39:24 05-08-12
Elapsed: 04 hrs 47 mins 54 secs