MutSigWithNozzleReport Execution Log 1:53 PM Sun Aug 5, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id KIRC
MutSigPreprocess1 maf1 dependentsValues8731223299639842879.tsv
MutSigPreprocess1 maf3 dependentsValues2930881018660638150.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 dependentsValues7253799835754112099.tsv
MutSigPreprocess1 build hg19
MutSigPreprocess1 context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
MutSigPreprocess1 context65_wig no_longer_needed
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id KIRC
MutSigRun3 gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
MutSigRun3 build hg19
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId KIRC
GDAC_MutSig_Report5 ind_set KIRC
Execution Times:
Submitted: 13:53:57 05-08-12
Completed:
Elapsed: 14 hrs 10 mins 21 secs

step 1. MutSigPreprocess [id: 142837] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:84
individual_set_id KIRC
maf1 dependentsValues8731223299639842879.tsv
maf2
maf3 dependentsValues2930881018660638150.tsv
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 dependentsValues7253799835754112099.tsv
wig2
wig3
wig4
build hg19
context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
context65_wig no_longer_needed
num_categories 4
target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 KIRC.mutation_preprocessing_report.txt
 KIRC.maf
 KIRC.coverage.prepare.txt
 .lsf.out
 KIRC.patients.txt
 stdout.txt
Execution Times:
Submitted: 13:53:57 05-08-12
Completed: 13:57:46 05-08-12
Elapsed: 00 hrs 03 mins 49 secs

step 2. ProcessCoverageForMutSig [id: 142838] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:72
coverage_prepare_file KIRC.coverage.prepare.txt
patient_list KIRC.patients.txt
mutation_list KIRC.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 KIRC.summed_coverage.fwi
 KIRC.summed_coverage.fwb
 KIRC.mutcategs.txt
 KIRC.mutcateg_discovery.txt
 KIRC.coverage.mat
 KIRC.covfiles
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 13:53:57 05-08-12
Completed: 15:39:01 05-08-12
Elapsed: 01 hrs 45 mins 04 secs

step 3. MutSigRun [id: 142839] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:153
individual_set_id KIRC
mutation_file KIRC.maf
coverage_file KIRC.coverage.mat
patient_file KIRC.patients.txt
category_file KIRC.mutcategs.txt
gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
build hg19
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg19
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file KIRC.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 KIRC.mutation_filtering_report.txt
 KIRC.MutSig_version.txt
 KIRC.per_exon.coverage.txt
 KIRC.covplot.png
 KIRC.covplot_hires.png
 KIRC.patients.counts_and_rates.txt
 KIRC.bargraphs.png
 KIRC.num_patients.txt
 KIRC.bargraphs_hires.png
 KIRC.mutcategs.txt
 KIRC.final_analysis_set.maf
 KIRC.per_gene.coverage.txt
 KIRC.mutation_breakdown.txt
 KIRC.per_gene.mutation_counts.txt
 KIRC.mutsig2.images
 KIRC.mutation_rates.txt
 KIRC.sample_sig_gene_table.txt
 KIRC.sig_genes.txt
 KIRC.sig_genesets.txt
 KIRC.sig_genesets_2.txt
 KIRC.cosmic_sig_genes.txt
 KIRC.cosmic_sig_genes2.txt
 KIRC.cosmic_mutations.txt_verbose.txt
 KIRC.cosmic_mutations.txt
 KIRC.clustered_muts.txt
 KIRC.gene_gene_correlations.txt
 KIRC.power_per_gene.total_coverage_histogram
 KIRC.power_per_gene.total_coverage.txt
 KIRC.power_per_gene.power_stats.txt
 KIRC.power_per_gene.power_stats_full.txt
 KIRC.power_per_gene.power_summary.txt
 KIRC.gene_coverage_plots
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 13:53:57 05-08-12
Completed: 04:02:38 06-08-12
Elapsed: 14 hrs 08 mins 41 secs

step 4. CoMut [id: 142840]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:4
individualSetId KIRC
patientCRFile KIRC.patients.counts_and_rates.txt
mafFile KIRC.final_analysis_set.maf
mutcategsFile KIRC.mutcategs.txt
sigGenesFile KIRC.sig_genes.txt
Output Files:
 KIRC_coMut.pdf
 KIRC_coMut.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:53:57 05-08-12
Completed: 04:03:31 06-08-12
Elapsed: 14 hrs 09 mins 34 secs

step 5. GDAC_MutSig_Report [id: 142841] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:13
bar_plot KIRC.bargraphs.png
breakdown_table KIRC.mutation_breakdown.txt
categories_table KIRC.mutation_rates.txt
coverage png KIRC.covplot.png
sig_table KIRC.sig_genes.txt
cosmic_table KIRC.cosmic_sig_genes.txt
cosmic_table2 KIRC.cosmic_sig_genes2.txt
cosmic_muts_table KIRC.cosmic_mutations.txt
cluster_table KIRC.clustered_muts.txt
geneset_table KIRC.sig_genesets.txt
genset_table2 KIRC.sig_genesets_2.txt
patients_c_and_r KIRC.patients.counts_and_rates.txt
ind_set KIRC
mutsig_version KIRC.MutSig_version.txt
coMut_plot_png KIRC_coMut.png
coMut_plot_pdf KIRC_coMut.pdf
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:53:57 05-08-12
Completed: 04:04:15 06-08-12
Elapsed: 14 hrs 10 mins 18 secs