| MutSigPreprocess1 individual_set_id | UCEC |
| MutSigPreprocess1 maf2 | MutSigPreprocess1.maf2.input.tsv |
| MutSigPreprocess1 maflabel1 | Broad |
| MutSigPreprocess1 maflabel2 | WashU |
| MutSigPreprocess1 maflabel3 | Baylor |
| MutSigPreprocess1 wig2 | MutSigPreprocess1.wig2.input.tsv |
| MutSigPreprocess1 build | hg19 |
| MutSigPreprocess1 context65_dir | /xchip/cga1/annotation/db/tracks/hg19/c65e |
| MutSigPreprocess1 context65_wig | no_longer_needed |
| MutSigPreprocess1 num_categories | 4 |
| MutSigPreprocess1 target_list | /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt |
| MutSigPreprocess1 paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 individual_set_id | UCEC |
| MutSigRun3 gene_list | /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt |
| MutSigRun3 build | hg19 |
| MutSigRun3 geneset_file | /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt |
| MutSigRun3 cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| MutSigRun3 refseq_file | /xchip/cga1/annotation/db/ucsc/hg19/R.mat |
| MutSigRun3 genome_dir | /xchip/cga1/annotation/db/ucsc/hg19 |
| MutSigRun3 param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 jobcount | 200 |
| CoMut4 individualSetId | UCEC |
| GDAC_MutSig_Report5 ind_set | UCEC |
| Execution Times: | |
| Submitted: | 14:24:26 10-08-12 |
| Completed: | |
| Elapsed: | 08 hrs 19 mins 04 secs |
step 1. MutSigPreprocess [id: 144939] preprocess patient list and mutations
urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:84
| individual_set_id | UCEC |
| maf1 | |
| maf2 | MutSigPreprocess1.maf2.input.tsv |
| maf3 | |
| maf4 | |
| maflabel1 | Broad |
| maflabel2 | WashU |
| maflabel3 | Baylor |
| maflabel4 | |
| wig1 | |
| wig2 | MutSigPreprocess1.wig2.input.tsv |
| wig3 | |
| wig4 | |
| build | hg19 |
| context65_dir | /xchip/cga1/annotation/db/tracks/hg19/c65e |
| context65_wig | no_longer_needed |
| num_categories | 4 |
| target_list | /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt |
| paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| Output Files: | |
| UCEC.mutation_preprocessing_report.txt | |
| UCEC.maf | |
| UCEC.patients.txt | |
| UCEC.coverage.prepare.txt | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 14:24:27 10-08-12 |
| Completed: | 14:32:25 10-08-12 |
| Elapsed: | 00 hrs 07 mins 58 secs |
step 2. ProcessCoverageForMutSig [id: 144940] processes coverage from wiggle files and does automatic category discovery
urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:72
| coverage_prepare_file | UCEC.coverage.prepare.txt |
| patient_list | UCEC.patients.txt |
| mutation_list | UCEC.maf |
| Execution Times: | |
| Submitted: | 14:24:27 10-08-12 |
| Completed: | 15:57:46 10-08-12 |
| Elapsed: | 01 hrs 33 mins 19 secs |
step 3. MutSigRun [id: 144941] perform MutSig calculations, generates output tables and report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:153
| individual_set_id | UCEC |
| mutation_file | UCEC.maf |
| coverage_file | UCEC.coverage.mat |
| patient_file | UCEC.patients.txt |
| category_file | UCEC.mutcategs.txt |
| gene_list | /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt |
| build | hg19 |
| geneset_file | /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt |
| cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| refseq_file | /xchip/cga1/annotation/db/ucsc/hg19/R.mat |
| genome_dir | /xchip/cga1/annotation/db/ucsc/hg19 |
| param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| mutation_preprocessing_report_file | UCEC.mutation_preprocessing_report.txt |
| jobcount | 200 |
| Execution Times: | |
| Submitted: | 14:24:27 10-08-12 |
| Completed: | 22:41:57 10-08-12 |
| Elapsed: | 08 hrs 17 mins 30 secs |
step 4. CoMut [id: 144942]
urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:4
| individualSetId | UCEC |
| patientCRFile | UCEC.patients.counts_and_rates.txt |
| mafFile | UCEC.final_analysis_set.maf |
| mutcategsFile | UCEC.mutcategs.txt |
| sigGenesFile | UCEC.sig_genes.txt |
| Output Files: | |
| UCEC_coMut.pdf | |
| .lsf.out | |
| UCEC_coMut.png | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 14:24:27 10-08-12 |
| Completed: | 22:42:58 10-08-12 |
| Elapsed: | 08 hrs 18 mins 30 secs |
step 5. GDAC_MutSig_Report [id: 144943] Somatic Mutation Report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:13
| bar_plot | UCEC.bargraphs.png |
| breakdown_table | UCEC.mutation_breakdown.txt |
| categories_table | UCEC.mutation_rates.txt |
| coverage png | UCEC.covplot.png |
| sig_table | UCEC.sig_genes.txt |
| cosmic_table | UCEC.cosmic_sig_genes.txt |
| cosmic_table2 | UCEC.cosmic_sig_genes2.txt |
| cosmic_muts_table | UCEC.cosmic_mutations.txt |
| cluster_table | UCEC.clustered_muts.txt |
| geneset_table | UCEC.sig_genesets.txt |
| genset_table2 | UCEC.sig_genesets_2.txt |
| patients_c_and_r | UCEC.patients.counts_and_rates.txt |
| ind_set | UCEC |
| mutsig_version | UCEC.MutSig_version.txt |
| coMut_plot_png | UCEC_coMut.png |
| coMut_plot_pdf | UCEC_coMut.pdf |
| Output Files: | |
| nozzle.RData | |
| nozzle.html | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 14:24:27 10-08-12 |
| Completed: | 22:43:28 10-08-12 |
| Elapsed: | 08 hrs 19 mins 01 secs |
