Clinical Features Time to Death AGE HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NEOADJUVANT.THERAPY nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p34.2) 26 (6%) 384 0.84255 1 0.0010266 0.331 1.0869e-08 4.33e-06 1 1 0.15921 1 Amp Peak 2(1p22.3) 53 (13%) 357 0.87775 1 0.22398 1 0.27142 1 0.75348 1 0.49953 1 Amp Peak 3(1q21.3) 160 (39%) 250 0.30798 1 0.00037503 0.126 0.044042 1 1 1 0.72871 1 Amp Peak 4(1q22) 170 (41%) 240 0.059366 1 3.0975e-05 0.011 0.015913 1 1 1 0.64659 1 Amp Peak 5(2p23.2) 72 (18%) 338 0.057429 1 0.0034468 1 2.6307e-07 0.000101 0.052579 1 0.456 1 Amp Peak 6(2q13) 66 (16%) 344 0.072 1 0.0012372 0.393 4.6915e-08 1.82e-05 0.7753 1 0.063632 1 Amp Peak 7(3p25.1) 48 (12%) 362 0.3207 1 0.00057284 0.189 3.3262e-07 0.000127 0.32442 1 0.37689 1 Amp Peak 8(3q26.2) 100 (24%) 310 0.21183 1 1.4699e-07 5.67e-05 2.6409e-18 1.14e-15 0.10852 1 0.025153 1 Amp Peak 9(3q26.2) 95 (23%) 315 0.050003 1 3.7535e-05 0.0132 7.902e-19 3.41e-16 0.13196 1 0.079776 1 Amp Peak 10(4p16.3) 27 (7%) 383 0.89497 1 6.9913e-06 0.00254 2.5324e-13 1.07e-10 0.5308 1 0.036373 1 Amp Peak 11(5p15.33) 48 (12%) 362 0.017909 1 0.0097857 1 6.5473e-12 2.72e-09 1 1 0.21554 1 Amp Peak 12(6p24.2) 58 (14%) 352 0.94874 1 0.00032734 0.111 1.5339e-10 6.26e-08 0.76143 1 0.32816 1 Amp Peak 13(6q16.3) 32 (8%) 378 0.41355 1 0.088537 1 0.0017928 0.563 0.69718 1 0.28857 1 Amp Peak 14(7q22.1) 47 (11%) 363 0.0042461 1 0.22578 1 0.086143 1 0.099789 1 0.37393 1 Amp Peak 15(8p11.22) 79 (19%) 331 0.0032347 0.974 0.14821 1 0.50574 1 0.78938 1 0.39125 1 Amp Peak 16(8p11.21) 98 (24%) 312 4.9837e-06 0.00182 0.9408 1 0.00056267 0.186 0.32139 1 0.18426 1 Amp Peak 17(8q24.21) 125 (30%) 285 0.00063721 0.208 0.14633 1 1.2007e-08 4.75e-06 0.42088 1 0.001346 0.427 Amp Peak 18(8q24.21) 132 (32%) 278 0.0068093 1 0.04885 1 1.2238e-09 4.91e-07 0.17494 1 0.0073171 1 Amp Peak 19(9p24.2) 33 (8%) 377 0.53411 1 0.080751 1 7.6953e-06 0.00279 0.24186 1 0.14508 1 Amp Peak 20(9q34.3) 20 (5%) 390 0.0031082 0.939 0.001106 0.354 9.116e-07 0.000344 1 1 0.060694 1 Amp Peak 21(10q22.2) 96 (23%) 314 0.3444 1 0.43664 1 0.12767 1 1 1 0.50367 1 Amp Peak 22(11p11.2) 23 (6%) 387 0.38371 1 0.00059796 0.197 3.3658e-08 1.31e-05 1 1 0.13866 1 Amp Peak 23(11q13.2) 33 (8%) 377 0.21949 1 0.20776 1 0.00010083 0.0348 0.84757 1 0.010769 1 Amp Peak 24(11q22.2) 24 (6%) 386 0.14494 1 0.0010005 0.323 9.7416e-05 0.0337 0.17425 1 0.027211 1 Amp Peak 25(12p13.33) 43 (10%) 367 0.39424 1 0.40467 1 0.0023971 0.736 1 1 0.13998 1 Amp Peak 26(12q13.11) 46 (11%) 364 0.54273 1 0.34838 1 0.0018064 0.565 1 1 0.59522 1 Amp Peak 27(12q13.2) 50 (12%) 360 0.51181 1 0.15734 1 9.1134e-06 0.00329 0.41876 1 0.7287 1 Amp Peak 28(14q24.3) 30 (7%) 380 0.7718 1 0.013424 1 3.5734e-07 0.000137 0.16037 1 0.078577 1 Amp Peak 29(14q32.33) 31 (8%) 379 0.11929 1 0.030345 1 1.5091e-06 0.000563 0.31746 1 0.086777 1 Amp Peak 30(15q26.3) 17 (4%) 393 0.78602 1 0.41076 1 0.17995 1 0.10751 1 0.15305 1 Amp Peak 31(16p11.2) 33 (8%) 377 0.1951 1 0.0014725 0.465 1.635e-14 6.93e-12 0.33683 1 0.0029064 0.886 Amp Peak 32(17p11.2) 14 (3%) 396 0.41375 1 0.48635 1 0.00039818 0.133 0.39006 1 0.05388 1 Amp Peak 33(17q11.2) 36 (9%) 374 0.014325 1 0.0030999 0.939 6.2523e-11 2.56e-08 0.26099 1 0.15838 1 Amp Peak 34(17q12) 46 (11%) 364 0.031877 1 4.5262e-05 0.0159 1.4387e-15 6.11e-13 0.5023 1 0.0018261 0.57 Amp Peak 35(17q21.32) 36 (9%) 374 0.012999 1 2.5205e-05 0.00902 3.7366e-06 0.00138 0.57827 1 0.15838 1 Amp Peak 36(18q11.2) 32 (8%) 378 0.0135 1 0.0012152 0.388 2.4879e-08 9.78e-06 0.43523 1 0.83257 1 Amp Peak 37(19p13.2) 49 (12%) 361 0.79928 1 2.2953e-10 9.32e-08 8.0976e-16 3.45e-13 0.073032 1 0.72743 1 Amp Peak 38(19p13.13) 53 (13%) 357 0.59358 1 4.8838e-11 2.01e-08 3.4634e-19 1.5e-16 0.1548 1 0.23855 1 Amp Peak 39(19q12) 49 (12%) 361 0.02326 1 8.837e-07 0.000334 6.0763e-24 2.67e-21 0.51386 1 3.6841e-05 0.013 Amp Peak 40(20p13) 50 (12%) 360 0.17061 1 0.013286 1 2.2435e-06 0.000832 0.14435 1 0.081851 1 Amp Peak 41(20q11.21) 65 (16%) 345 0.90416 1 0.00018675 0.0639 7.3721e-20 3.2e-17 0.47059 1 0.02866 1 Amp Peak 42(20q13.12) 67 (16%) 343 0.10102 1 7.4447e-05 0.0259 3.1481e-18 1.35e-15 0.15171 1 0.020545 1 Amp Peak 43(20q13.33) 68 (17%) 342 0.45245 1 0.00019507 0.0665 1.9525e-11 8.06e-09 0.1179 1 0.02211 1 Del Peak 1(1p36.31) 40 (10%) 370 0.36773 1 0.0023324 0.721 0.00040296 0.134 0.47599 1 0.17897 1 Del Peak 2(1p36.11) 46 (11%) 364 0.14966 1 0.00062913 0.206 5.6488e-10 2.27e-07 0.86828 1 0.27968 1 Del Peak 3(2q22.1) 26 (6%) 384 3.3876e-05 0.012 0.030841 1 0.0030736 0.934 0.027575 1 1 1 Del Peak 4(2q37.3) 24 (6%) 386 0.66808 1 0.0072631 1 0.11944 1 0.82594 1 0.22398 1 Del Peak 5(3p14.2) 40 (10%) 370 0.42466 1 2.9715e-05 0.0106 4.562e-10 1.84e-07 0.85965 1 0.17897 1 Del Peak 6(4p16.3) 45 (11%) 365 0.12471 1 0.00013238 0.0454 3.7952e-11 1.56e-08 0.49948 1 0.36562 1 Del Peak 7(4q22.1) 46 (11%) 364 0.028968 1 0.00076283 0.249 1.1848e-12 4.96e-10 0.13234 1 0.27968 1 Del Peak 8(4q34.3) 63 (15%) 347 0.26933 1 6.4824e-05 0.0227 3.0388e-17 1.3e-14 0.56095 1 0.0070305 1 Del Peak 9(5q11.2) 53 (13%) 357 0.45846 1 7.9812e-05 0.0277 1.1272e-21 4.91e-19 1 1 0.016866 1 Del Peak 10(6q26) 24 (6%) 386 0.5545 1 0.090607 1 0.00087635 0.284 0.65221 1 1 1 Del Peak 11(7p22.3) 44 (11%) 366 0.042632 1 0.00011848 0.0408 2.6525e-10 1.07e-07 1 1 0.042676 1 Del Peak 12(7q11.22) 20 (5%) 390 0.39514 1 0.006217 1 0.00025397 0.0863 1 1 0.18382 1 Del Peak 13(7q36.1) 40 (10%) 370 0.20318 1 1.1469e-06 0.00043 6.8085e-20 2.96e-17 0.47599 1 0.0017322 0.546 Del Peak 14(8p23.3) 62 (15%) 348 0.65058 1 0.0060532 1 5.7131e-22 2.5e-19 0.65891 1 0.0064994 1 Del Peak 15(8p11.22) 31 (8%) 379 0.52148 1 0.0010819 0.347 1.6853e-12 7.04e-10 0.84219 1 0.033013 1 Del Peak 16(9p23) 36 (9%) 374 0.43866 1 0.00032169 0.109 2.9502e-08 1.15e-05 0.70884 1 0.069178 1 Del Peak 17(9q34.11) 75 (18%) 335 0.46366 1 2.5125e-08 9.85e-06 1.515e-10 6.2e-08 0.68148 1 0.026952 1 Del Peak 18(10q21.2) 17 (4%) 393 0.77574 1 0.34706 1 0.027381 1 0.79292 1 0.39229 1 Del Peak 19(10q23.31) 36 (9%) 374 0.41434 1 0.18758 1 0.1212 1 0.13289 1 0.31482 1 Del Peak 20(11p15.5) 54 (13%) 356 0.013373 1 2.259e-06 0.000836 2.6327e-12 1.1e-09 0.34995 1 0.0038067 1 Del Peak 21(11q14.1) 38 (9%) 372 0.0076606 1 0.00034005 0.115 1.6335e-08 6.44e-06 0.47188 1 0.11551 1 Del Peak 22(11q24.2) 48 (12%) 362 0.0023633 0.728 7.0335e-05 0.0245 7.8376e-09 3.13e-06 0.51188 1 0.051256 1 Del Peak 23(12q23.1) 19 (5%) 391 0.58875 1 0.049504 1 0.022267 1 0.80172 1 0.27929 1 Del Peak 24(12q24.33) 26 (6%) 384 0.49597 1 0.00039792 0.133 3.8131e-06 0.0014 0.38873 1 0.25327 1 Del Peak 25(13q11) 43 (10%) 367 0.30457 1 0.00034625 0.116 2.0001e-06 0.000744 0.39114 1 0.46015 1 Del Peak 26(13q14.2) 45 (11%) 365 0.37627 1 0.0027729 0.849 0.013801 1 0.31026 1 1 1 Del Peak 27(14q13.1) 34 (8%) 376 0.0096556 1 3.6503e-05 0.0129 6.3023e-07 0.000239 1 1 0.03797 1 Del Peak 28(15q15.1) 73 (18%) 337 0.19792 1 1.2619e-06 0.000472 1.7332e-10 7.05e-08 0.16651 1 0.07405 1 Del Peak 29(15q23) 57 (14%) 353 0.10831 1 5.0675e-06 0.00185 1.9108e-11 7.91e-09 0.54351 1 0.07322 1 Del Peak 30(16p13.3) 43 (10%) 367 0.0039803 1 9.225e-07 0.000347 4.0119e-07 0.000153 0.39114 1 0.85388 1 Del Peak 31(16q22.3) 95 (23%) 315 0.16904 1 8.698e-08 3.37e-05 3.4568e-16 1.48e-13 0.61635 1 0.043122 1 Del Peak 32(16q23.1) 100 (24%) 310 0.13301 1 1.2719e-08 5.02e-06 3.6191e-19 1.56e-16 0.5378 1 0.0034328 1 Del Peak 33(17p13.3) 61 (15%) 349 0.20113 1 2.1399e-05 0.00768 1.1738e-11 4.87e-09 0.55205 1 0.0038171 1 Del Peak 34(17p11.2) 71 (17%) 339 0.13526 1 4.1958e-07 0.000159 2.7979e-22 1.23e-19 0.33004 1 0.0041513 1 Del Peak 35(17p11.2) 64 (16%) 346 0.42985 1 2.365e-06 0.000873 3.3287e-14 1.41e-11 1 1 0.085067 1 Del Peak 36(17q11.2) 60 (15%) 350 0.93759 1 1.2766e-05 0.0046 3.1886e-09 1.28e-06 0.37236 1 0.14786 1 Del Peak 37(17q21.2) 61 (15%) 349 0.57977 1 5.3733e-06 0.00196 2.8745e-10 1.16e-07 0.23351 1 0.054417 1 Del Peak 38(18q23) 50 (12%) 360 0.07495 1 0.0034198 1 1.1413e-07 4.42e-05 0.023812 1 0.7287 1 Del Peak 39(19p13.3) 95 (23%) 315 0.034605 1 3.1368e-13 1.32e-10 2.8615e-42 1.26e-39 0.45216 1 0.001928 0.6 Del Peak 40(19q13.43) 28 (7%) 382 0.0091642 1 0.00082021 0.267 1.1409e-08 4.53e-06 0.67719 1 0.040541 1 Del Peak 41(20p12.1) 19 (5%) 391 0.53721 1 0.0078048 1 0.15514 1 1 1 1 1 Del Peak 42(20q13.12) 6 (1%) 404 0.53556 1 0.051708 1 0.65368 1 0.085491 1 1 1 Del Peak 43(22q11.1) 41 (10%) 369 0.78676 1 0.0022485 0.697 0.074849 1 0.29623 1 0.34562 1 Del Peak 44(22q12.1) 51 (12%) 359 0.47472 1 0.01725 1 0.025427 1 0.20016 1 0.17097 1 Del Peak 45(22q13.32) 79 (19%) 331 0.057234 1 1.839e-07 7.08e-05 2.4348e-13 1.03e-10 0.42245 1 0.06055 1