MutSigWithNozzleReport Execution Log 4:21 PM Thu Aug 16, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id CESC
MutSigPreprocess1 maf1 MutSigPreprocess1.maf1.input.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 MutSigPreprocess1.wig1.input.tsv
MutSigPreprocess1 build hg19
MutSigPreprocess1 context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
MutSigPreprocess1 build_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id CESC
MutSigRun3 gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
MutSigRun3 build hg19
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
MutSigRun3 build_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId CESC
GDAC_MutSig_Report6 ind_set CESC
Execution Times:
Submitted: 16:21:59 16-08-12
Completed:
Elapsed: 04 hrs 45 mins 24 secs

step 1. MutSigPreprocess [id: 146744] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:90
individual_set_id CESC
maf1 MutSigPreprocess1.maf1.input.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 MutSigPreprocess1.wig1.input.tsv
wig2
wig3
wig4
build hg19
context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
build_dir /xchip/cga1/annotation/db/ucsc/hg19
num_categories 4
target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 CESC.mutation_preprocessing_report.txt
 CESC.maf
 CESC.patients.txt
 CESC.coverage.prepare.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 16:23:17 16-08-12
Elapsed: 00 hrs 01 mins 18 secs

step 2. ProcessCoverageForMutSig [id: 146745] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:77
coverage_prepare_file CESC.coverage.prepare.txt
patient_list CESC.patients.txt
mutation_list CESC.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 CESC.summed_coverage.fwi
 CESC.summed_coverage.fwb
 CESC.mutcategs.txt
 CESC.mutcateg_discovery.txt
 CESC.coverage.mat
 CESC.covfiles
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 16:42:43 16-08-12
Elapsed: 00 hrs 20 mins 43 secs

step 3. MutSigRun [id: 146746] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:160
individual_set_id CESC
mutation_file CESC.maf
coverage_file CESC.coverage.mat
patient_file CESC.patients.txt
category_file CESC.mutcategs.txt
gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
build hg19
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
build_dir /xchip/cga1/annotation/db/ucsc/hg19
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file CESC.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 CESC.mutation_filtering_report.txt
 CESC.MutSig_version.txt
 CESC.per_exon.coverage.txt
 CESC.covplot.png
 CESC.covplot_hires.png
 CESC.patients.counts_and_rates.txt
 CESC.bargraphs.png
 CESC.bargraphs_hires.png
 CESC.num_patients.txt
 CESC.final_analysis_set.maf
 CESC.mutcategs.txt
 CESC.per_gene.coverage.txt
 CESC.mutation_breakdown.txt
 CESC.per_gene.mutation_counts.txt
 CESC.mutsig2.images
 CESC.mutation_rates.txt
 CESC.sample_sig_gene_table.txt
 CESC.sig_genes.txt
 CESC.sig_genesets.txt
 CESC.sig_genesets_2.txt
 CESC.cosmic_sig_genes2.txt
 CESC.cosmic_mutations.txt
 CESC.cosmic_mutations.txt_verbose.txt
 CESC.cosmic_sig_genes.txt
 CESC.gene_gene_correlations.txt
 CESC.clustered_muts.txt
 CESC.power_per_gene.total_coverage.txt
 CESC.power_per_gene.total_coverage_histogram
 CESC.power_per_gene.power_stats.txt
 CESC.power_per_gene.power_stats_full.txt
 CESC.power_per_gene.power_summary.txt
 CESC.gene_coverage_plots
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 21:03:35 16-08-12
Elapsed: 04 hrs 41 mins 36 secs

step 4. CoMut [id: 146747]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:7
individualSetId CESC
patientCRFile CESC.patients.counts_and_rates.txt
mafFile CESC.final_analysis_set.maf
mutcategsFile CESC.mutcategs.txt
sigGenesFile CESC.sig_genes.txt
Output Files:
 CESC_coMut.pdf
 CESC_coMut.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 21:05:03 16-08-12
Elapsed: 04 hrs 43 mins 04 secs

step 5. GenerateStickFigures [id: 146748]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00497:4
maf CESC.final_analysis_set.maf
sig_genes CESC.sig_genes.txt
Output Files:
 PIK3CA.stick_fig.txt
 PIK3CA.stick_fig.png
 MAPK1.stick_fig.txt
 generatedStickFigurePaths.txt
 MAPK1.stick_fig.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 21:06:19 16-08-12
Elapsed: 04 hrs 44 mins 19 secs

step 6. GDAC_MutSig_Report [id: 146749] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:16
bar_plot CESC.bargraphs.png
breakdown_table CESC.mutation_breakdown.txt
categories_table CESC.mutation_rates.txt
coverage png CESC.covplot.png
sig_table CESC.sig_genes.txt
cosmic_table CESC.cosmic_sig_genes.txt
cosmic_table2 CESC.cosmic_sig_genes2.txt
cosmic_muts_table CESC.cosmic_mutations.txt
cluster_table CESC.clustered_muts.txt
geneset_table CESC.sig_genesets.txt
genset_table2 CESC.sig_genesets_2.txt
patients_c_and_r CESC.patients.counts_and_rates.txt
ind_set CESC
mutsig_version CESC.MutSig_version.txt
coMut_plot_png CESC_coMut.png
coMut_plot_pdf CESC_coMut.pdf
stick_figures_path generatedStickFigurePaths.txt
maf_path CESC.final_analysis_set.maf
mut_pre_rep_path CESC.mutation_preprocessing_report.txt
mut_filt_rep_path CESC.mutation_filtering_report.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:21:59 16-08-12
Completed: 21:07:21 16-08-12
Elapsed: 04 hrs 45 mins 22 secs