MutSigWithNozzleReport Execution Log 8:31 AM Fri Aug 10, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id OV
MutSigPreprocess1 maf1 MutSigPreprocess1.maf1.input.tsv
MutSigPreprocess1 maf2 MutSigPreprocess1.maf2.input.tsv
MutSigPreprocess1 maf3 MutSigPreprocess1.maf3.input.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 MutSigPreprocess1.wig1.input.tsv
MutSigPreprocess1 wig2 MutSigPreprocess1.wig2.input.tsv
MutSigPreprocess1 wig3 MutSigPreprocess1.wig3.input.tsv
MutSigPreprocess1 build hg18
MutSigPreprocess1 context65_dir /xchip/cga1/lawrence/db/context65
MutSigPreprocess1 build_dir /xchip/cga1/annotation/db/ucsc/hg18
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id OV
MutSigRun3 gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
MutSigRun3 build hg18
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
MutSigRun3 build_dir /xchip/cga1/annotation/db/ucsc/hg18
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId OV
GDAC_MutSig_Report6 ind_set OV
Execution Times:
Submitted: 08:31:17 10-08-12
Completed:
Elapsed: 07 hrs 10 mins 20 secs

step 1. MutSigPreprocess [id: 144827] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:90
individual_set_id OV
maf1 MutSigPreprocess1.maf1.input.tsv
maf2 MutSigPreprocess1.maf2.input.tsv
maf3 MutSigPreprocess1.maf3.input.tsv
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 MutSigPreprocess1.wig1.input.tsv
wig2 MutSigPreprocess1.wig2.input.tsv
wig3 MutSigPreprocess1.wig3.input.tsv
wig4
build hg18
context65_dir /xchip/cga1/lawrence/db/context65
build_dir /xchip/cga1/annotation/db/ucsc/hg18
num_categories 4
target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 OV.mutation_preprocessing_report.txt
 OV.patients.txt
 OV.maf
 OV.coverage.prepare.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 08:32:46 10-08-12
Elapsed: 00 hrs 01 mins 29 secs

step 2. ProcessCoverageForMutSig [id: 144828] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:77
coverage_prepare_file OV.coverage.prepare.txt
patient_list OV.patients.txt
mutation_list OV.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 OV.summed_coverage.fwi
 OV.summed_coverage.fwb
 OV.mutcateg_discovery.txt
 OV.mutcategs.txt
 OV.coverage.mat
 OV.covfiles
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 09:09:58 10-08-12
Elapsed: 00 hrs 38 mins 40 secs

step 3. MutSigRun [id: 144829] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:160
individual_set_id OV
mutation_file OV.maf
coverage_file OV.coverage.mat
patient_file OV.patients.txt
category_file OV.mutcategs.txt
gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
build hg18
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
build_dir /xchip/cga1/annotation/db/ucsc/hg18
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file OV.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 OV.mutation_filtering_report.txt
 OV.MutSig_version.txt
 OV.per_exon.coverage.txt
 OV.covplot.png
 OV.patients.counts_and_rates.txt
 OV.covplot_hires.png
 OV.bargraphs.png
 OV.num_patients.txt
 OV.bargraphs_hires.png
 OV.final_analysis_set.maf
 OV.mutcategs.txt
 OV.per_gene.coverage.txt
 OV.per_gene.mutation_counts.txt
 OV.mutation_breakdown.txt
 OV.mutsig2.images
 OV.sample_sig_gene_table.txt
 OV.mutation_rates.txt
 OV.sig_genes.txt
 OV.sig_genesets.txt
 OV.sig_genesets_2.txt
 OV.cosmic_sig_genes.txt
 OV.cosmic_mutations.txt_verbose.txt
 OV.cosmic_sig_genes2.txt
 OV.cosmic_mutations.txt
 OV.clustered_muts.txt
 OV.gene_gene_correlations.txt
 OV.power_per_gene.total_coverage.txt
 OV.power_per_gene.total_coverage_histogram
 OV.power_per_gene.power_stats.txt
 OV.power_per_gene.power_stats_full.txt
 OV.power_per_gene.power_summary.txt
 OV.gene_coverage_plots
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 15:39:49 10-08-12
Elapsed: 07 hrs 08 mins 32 secs

step 4. CoMut [id: 144830]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:7
individualSetId OV
patientCRFile OV.patients.counts_and_rates.txt
mafFile OV.final_analysis_set.maf
mutcategsFile OV.mutcategs.txt
sigGenesFile OV.sig_genes.txt
Output Files:
 OV_coMut.png
 OV_coMut.pdf
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 15:40:34 10-08-12
Elapsed: 07 hrs 09 mins 16 secs

step 5. GenerateStickFigures [id: 144831]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00497:4
maf OV.final_analysis_set.maf
sig_genes OV.sig_genes.txt
Output Files:
 generatedStickFigurePaths.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 15:41:04 10-08-12
Elapsed: 07 hrs 09 mins 47 secs

step 6. GDAC_MutSig_Report [id: 144832] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:16
bar_plot OV.bargraphs.png
breakdown_table OV.mutation_breakdown.txt
categories_table OV.mutation_rates.txt
coverage png OV.covplot.png
sig_table OV.sig_genes.txt
cosmic_table OV.cosmic_sig_genes.txt
cosmic_table2 OV.cosmic_sig_genes2.txt
cosmic_muts_table OV.cosmic_mutations.txt
cluster_table OV.clustered_muts.txt
geneset_table OV.sig_genesets.txt
genset_table2 OV.sig_genesets_2.txt
patients_c_and_r OV.patients.counts_and_rates.txt
ind_set OV
mutsig_version OV.MutSig_version.txt
coMut_plot_png OV_coMut.png
coMut_plot_pdf OV_coMut.pdf
stick_figures_path generatedStickFigurePaths.txt
maf_path OV.final_analysis_set.maf
mut_pre_rep_path OV.mutation_preprocessing_report.txt
mut_filt_rep_path OV.mutation_filtering_report.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 08:31:17 10-08-12
Completed: 15:41:35 10-08-12
Elapsed: 07 hrs 10 mins 17 secs