Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.016 0.146 -9999.0 0.0 -0.335 48.0 48.0 MAP3K8 0.002 0.111 -9999.0 0.0 -0.423 32.0 32.0 FOS 0.019 0.099 -9999.0 0.0 -0.397 9.0 9.0 PRKCA 0.025 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.02 0.032 -9999.0 0.0 -0.441 1.0 1.0 HRAS 0.031 0.036 -9999.0 0.0 -0.423 3.0 3.0 PRKCB -0.002 0.006 -9999.0 0.0 -0.016 73.0 73.0 NRAS 0.029 0.05 -9999.0 0.0 -0.422 6.0 6.0 RAS family/GTP 0.05 0.055 -9999.0 0.0 -0.23 15.0 15.0 MAPK3 0.027 0.07 -9999.0 0.0 -0.454 6.0 6.0 MAP2K1 0.008 0.066 -9999.0 0.0 -0.249 9.0 9.0 ELK1 0.024 0.038 -9999.0 0.0 -0.42 2.0 2.0 BRAF 0.005 0.05 -9999.0 0.0 -0.353 8.0 8.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 73.0 73.0 MAPK1 0.012 0.1 -9999.0 0.0 -0.405 19.0 19.0 RAF1 0.01 0.023 -9999.0 0.0 -0.241 1.0 1.0 KRAS 0.027 0.057 -9999.0 0.0 -0.421 8.0 8.0