Clinical Features Time to Death AGE GENDER KARNOFSKY.PERFORMANCE.SCORE PATHOLOGY.T PATHOLOGY.N PATHOLOGICSPREAD(M) TUMOR.STAGE NEOADJUVANT.THERAPY nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q VHL 146 (50%) 147 0.82034 1 0.011376 1 0.086758 1 0.35871 1 0.43822 1 0.76038 1 0.73133 1 0.50862 1 1 1 KDM5C 18 (6%) 275 0.080341 1 0.20614 1 0.0048565 1 NA NA 0.6222 1 0.51612 1 1 1 0.85621 1 1 1 PBRM1 98 (33%) 195 0.4438 1 0.3385 1 0.069817 1 0.35029 1 0.73092 1 1 1 0.20117 1 0.21753 1 0.26002 1 RRAD 4 (1%) 289 0.083589 1 0.80614 1 0.12314 1 NA NA 0.061282 1 0.21076 1 0.43703 1 0.070211 1 1 1 SV2C 3 (1%) 290 0.73052 1 0.020511 1 1 1 NA NA 1 1 1 1 1 1 1 1 1 1 TOR1A 3 (1%) 290 0.053193 1 0.70446 1 1 1 NA NA 1 1 0.075342 1 1 1 1 1 1 1 BAP1 27 (9%) 266 0.013078 1 0.82828 1 0.0096062 1 NA NA 0.0029452 1 0.62679 1 0.00089531 0.691 0.00011084 0.0858 0.25254 1 SETD2 32 (11%) 261 0.94922 1 0.11002 1 0.24399 1 NA NA 0.22861 1 0.60458 1 0.051861 1 0.18363 1 0.29406 1 PTEN 15 (5%) 278 0.87012 1 0.10383 1 1 1 NA NA 0.48864 1 0.065747 1 1 1 0.59201 1 0.14633 1 PIK3CA 14 (5%) 279 0.79651 1 0.38721 1 0.56993 1 NA NA 0.15192 1 0.55498 1 1 1 0.25135 1 1 1 STAG3L2 6 (2%) 287 0.25228 1 0.1149 1 1 1 NA NA 0.41473 1 1 1 0.57895 1 0.33366 1 1 1 MTOR 24 (8%) 269 0.1231 1 0.20329 1 0.11937 1 NA NA 0.2977 1 0.060205 1 1 1 0.34624 1 1 1 EBPL 6 (2%) 287 0.4799 1 0.52653 1 0.0016133 1 NA NA 0.11682 1 1 1 1 1 0.064611 1 1 1 KANK3 6 (2%) 287 0.73341 1 0.51324 1 1 1 NA NA 0.5099 1 1 1 1 1 0.69638 1 1 1 NUDT11 3 (1%) 290 0.60037 1 1.5794e-24 1.23e-21 0.55397 1 NA NA 0.71834 1 NA NA 1 1 0.47899 1 1 1 ANKRD36 10 (3%) 283 0.28392 1 0.33946 1 1 1 NA NA 0.39061 1 1 1 1 1 0.63724 1 1 1 ZCCHC3 3 (1%) 290 0.39158 1 0.82928 1 0.55397 1 NA NA 0.37387 1 1 1 1 1 0.81142 1 1 1 FAM174B 3 (1%) 290 0.47617 1 0.66837 1 1 1 NA NA 0.091728 1 NA NA 1 1 0.072354 1 1 1 TSPAN19 4 (1%) 289 0.31942 1 0.46657 1 1 1 NA NA 0.45804 1 1 1 0.43703 1 0.22259 1 1 1 DACH2 7 (2%) 286 0.97163 1 0.70042 1 0.24229 1 NA NA 1 1 0.32791 1 0.23565 1 0.63077 1 0.070208 1 KRTAP1-1 3 (1%) 290 0.29558 1 0.9701 1 0.041379 1 NA NA 0.091728 1 NA NA 0.34955 1 0.14634 1 1 1 UQCRFS1 3 (1%) 290 0.32077 1 0.51808 1 0.27848 1 NA NA 0.045235 1 1 1 1 1 0.055412 1 1 1 VCX2 3 (1%) 290 0.29282 1 0.058018 1 1 1 NA NA 0.14269 1 1 1 0.34955 1 0.11749 1 1 1 CR1 11 (4%) 282 0.58157 1 0.93558 1 0.52316 1 NA NA 0.83066 1 1 1 0.64531 1 0.69157 1 1 1 KRT1 5 (2%) 288 0.0050564 1 0.032239 1 0.3462 1 NA NA 0.17213 1 1 1 1 1 0.072041 1 1 1 ABCB1 8 (3%) 285 0.11603 1 0.58179 1 0.71798 1 NA NA 0.88183 1 1 1 0.60309 1 0.784 1 1 1 MADCAM1 4 (1%) 289 0.35688 1 0.75065 1 0.12314 1 NA NA 0.0204 1 1 1 0.087133 1 0.0047536 1 1 1 WDR52 9 (3%) 284 0.96703 1 0.39545 1 0.72392 1 NA NA 0.64744 1 1 1 0.34179 1 0.84225 1 1 1 TPTE2 7 (2%) 286 0.29987 1 0.30914 1 1 1 NA NA 0.47979 1 1 1 0.59949 1 0.59582 1 1 1 OR5H1 4 (1%) 289 0.91866 1 0.5238 1 0.61241 1 NA NA 0.60567 1 1 1 1 1 0.6701 1 1 1 PCDHGA8 4 (1%) 289 0.25091 1 0.20698 1 1 1 NA NA 1 1 1 1 1 1 0.76764 1 1 1 POLDIP2 4 (1%) 289 0.45793 1 0.70482 1 1 1 NA NA 0.45804 1 1 1 0.43703 1 0.35681 1 1 1 CCNB2 5 (2%) 288 0.78386 1 0.459 1 1 1 NA NA 1 1 1 1 1 1 0.91054 1 1 1 NFE2L2 5 (2%) 288 0.16281 1 0.16234 1 1 1 NA NA 0.82709 1 1 1 0.513 1 0.61867 1 1 1 BAGE2 4 (1%) 289 0.96052 1 0.66701 1 0.61241 1 NA NA 0.79604 1 1 1 1 1 0.58946 1 1 1 RECQL5 6 (2%) 287 0.050734 1 0.57474 1 0.18769 1 NA NA 0.60675 1 0.32791 1 0.18326 1 0.35869 1 1 1 SCAI 7 (2%) 286 0.46149 1 0.58304 1 0.42796 1 NA NA 0.24619 1 1 1 0.59949 1 0.79252 1 1 1 GFRAL 5 (2%) 288 0.65486 1 0.039887 1 1 1 NA NA 0.096039 1 1 1 1 1 0.28805 1 1 1 NPNT 6 (2%) 287 0.080587 1 0.22183 1 0.66842 1 NA NA 0.3421 1 1 1 1 1 0.21858 1 1 1 MSN 4 (1%) 289 0.6302 1 0.57771 1 1 1 NA NA 0.18951 1 1 1 1 1 0.46413 1 1 1 CNTNAP4 9 (3%) 284 0.48544 1 0.50035 1 0.72392 1 NA NA 0.51005 1 1 1 1 1 0.51285 1 1 1 GRIN2B 11 (4%) 282 0.95184 1 0.75535 1 1 1 NA NA 0.83066 1 1 1 1 1 0.58662 1 1 1 DNAH9 17 (6%) 276 0.5353 1 0.98645 1 0.30021 1 NA NA 0.7829 1 0.51612 1 0.70988 1 0.5916 1 1 1 SP8 3 (1%) 290 0.25159 1 0.051831 1 1 1 NA NA 1 1 1 1 1 1 1 1 1 1 ZNF800 6 (2%) 287 0.16613 1 0.59874 1 1 1 NA NA 1 1 1 1 0.57895 1 0.80575 1 1 1 SFRS15 9 (3%) 284 0.56444 1 0.80377 1 0.72392 1 NA NA 0.64744 1 1 1 1 1 0.45868 1 1 1 UGT2A3 4 (1%) 289 0.5287 1 0.35418 1 0.61241 1 NA NA 1 1 1 1 0.087133 1 0.18894 1 1 1 LPAR4 4 (1%) 289 0.53396 1 0.45668 1 0.61241 1 NA NA 1 1 1 1 1 1 0.76764 1 1 1 SPAM1 5 (2%) 288 0.26962 1 0.19215 1 0.66137 1 NA NA 0.096039 1 1 1 1 1 0.28805 1 1 1 LMO4 3 (1%) 290 0.9015 1 0.075188 1 1 1 NA NA 0.51851 1 1 1 1 1 0.38008 1 1 1 RNF115 4 (1%) 289 0.61063 1 0.72689 1 0.61241 1 NA NA 0.79604 1 1 1 1 1 1 1 1 1 ZYG11B 6 (2%) 287 0.31696 1 0.0036708 1 1 1 NA NA 0.86311 1 1 1 1 1 0.86441 1 1 1 MARCKS 3 (1%) 290 0.29756 1 0.11325 1 0.27848 1 NA NA 0.091728 1 1 1 1 1 0.072354 1 1 1 NBPF10 20 (7%) 273 0.23698 1 0.32071 1 0.15069 1 NA NA 0.20226 1 0.13893 1 0.035297 1 0.13417 1 1 1 WASL 5 (2%) 288 0.61206 1 0.22477 1 0.3462 1 NA NA 0.3253 1 1 1 1 1 0.083016 1 1 1 PRB3 3 (1%) 290 NA NA 0.1234 1 0.55397 1 NA NA 1 1 0.075342 1 1 1 1 1 1 1 MED12L 8 (3%) 285 0.017954 1 0.87469 1 1 1 NA NA 0.88183 1 1 1 0.28887 1 0.62482 1 1 1 NF2 6 (2%) 287 0.42351 1 0.8527 1 0.42285 1 NA NA 0.17656 1 0.27147 1 0.57895 1 0.20275 1 1 1 PRB4 3 (1%) 290 NA NA 0.70976 1 0.041379 1 NA NA 0.51851 1 1 1 1 1 0.38008 1 1 1 FBXO43 5 (2%) 288 1.2734e-13 9.87e-11 0.62116 1 1 1 NA NA 0.44551 1 1 1 0.513 1 1 1 1 1 KCNH7 8 (3%) 285 0.78701 1 0.95009 1 1 1 NA NA 0.52935 1 0.21076 1 0.60309 1 0.71481 1 1 1 TP53 9 (3%) 284 0.045413 1 0.091003 1 0.28461 1 NA NA 0.031982 1 0.32791 1 1 1 0.046064 1 1 1 PRIM2 5 (2%) 288 0.10476 1 0.7963 1 0.3462 1 NA NA 0.096039 1 1 1 1 1 0.28805 1 1 1 PTPN18 4 (1%) 289 0.41587 1 0.34938 1 1 1 NA NA 0.25775 1 1 1 1 1 0.40703 1 1 1 SLC2A14 3 (1%) 290 0.71332 1 0.89736 1 1 1 NA NA 0.51851 1 1 1 1 1 0.38008 1 1 1 DPP10 6 (2%) 287 0.36865 1 0.90233 1 1 1 NA NA 0.2248 1 1 1 0.18326 1 1 1 1 1 OR10G7 5 (2%) 288 0.049781 1 0.30133 1 1 1 NA NA 0.56784 1 1 1 0.513 1 0.054191 1 1 1 ZKSCAN1 4 (1%) 289 0.55777 1 0.67515 1 0.61241 1 NA NA 0.18951 1 1 1 1 1 0.46413 1 1 1 MYO6 3 (1%) 290 NA NA 0.19638 1 0.55397 1 NA NA 0.37387 1 NA NA 1 1 0.81142 1 1 1 MAGEC1 7 (2%) 286 0.58613 1 0.1941 1 0.24229 1 NA NA 0.87814 1 0.32791 1 0.59949 1 0.19766 1 1 1 KRTAP4-1 3 (1%) 290 0.92653 1 0.17302 1 0.041379 1 NA NA 0.71834 1 1 1 1 1 0.47899 1 1 1 POTEC 10 (3%) 283 0.38637 1 0.03516 1 1 1 NA NA 0.81043 1 1 1 1 1 0.75254 1 1 1 RPUSD2 3 (1%) 290 NA NA 0.78941 1 1 1 NA NA 1 1 1 1 1 1 1 1 1 1 SERPINB5 3 (1%) 290 0.76353 1 0.76501 1 0.55397 1 NA NA 0.37387 1 1 1 1 1 0.81142 1 1 1 ADCY8 5 (2%) 288 0.70645 1 0.5818 1 0.16703 1 NA NA 0.26248 1 0.075342 1 0.513 1 0.09458 1 1 1 COL11A1 8 (3%) 285 0.94558 1 0.54631 1 0.26907 1 NA NA 0.78298 1 0.27147 1 0.60309 1 0.59634 1 1 1 CLYBL 4 (1%) 289 0.37471 1 0.64628 1 0.30173 1 NA NA 0.12396 1 1 1 1 1 0.12815 1 1 1 SPEN 14 (5%) 279 0.31224 1 0.56132 1 1 1 NA NA 0.63182 1 0.13893 1 0.70204 1 0.59951 1 1 1 MSR1 5 (2%) 288 0.15647 1 0.35324 1 1 1 NA NA 0.3253 1 0.028633 1 0.513 1 0.10687 1 1 1 ADAMTS20 7 (2%) 286 0.16326 1 0.24343 1 0.69753 1 NA NA 0.87814 1 1 1 0.052283 1 0.078137 1 1 1 C15ORF26 4 (1%) 289 0.22081 1 0.065224 1 0.30173 1 NA NA 0.45804 1 NA NA 0.087133 1 0.18894 1 1 1 ZFP112 5 (2%) 288 0.3626 1 0.87612 1 0.16703 1 NA NA 0.44551 1 1 1 1 1 0.83066 1 1 1 CLN8 3 (1%) 290 0.46958 1 0.19347 1 0.27848 1 NA NA 0.37387 1 1 1 1 1 0.81142 1 1 1 RARA 4 (1%) 289 0.46217 1 0.55353 1 1 1 NA NA 0.60567 1 1 1 1 1 0.6701 1 1 1 LILRB3 3 (1%) 290 0.80301 1 0.9202 1 0.27848 1 NA NA 0.24366 1 NA NA 0.34955 1 0.5832 1 1 1 TMEM184C 4 (1%) 289 0.017158 1 0.00039122 0.302 1 1 NA NA 0.79604 1 1 1 1 1 1 1 1 1 STAG2 10 (3%) 283 0.95063 1 0.0086737 1 1 1 NA NA 0.072736 1 1 1 1 1 0.078163 1 1 1 SPRYD5 4 (1%) 289 0.51593 1 0.45379 1 1 1 NA NA 0.60567 1 1 1 1 1 0.6701 1 1 1 SDR16C5 4 (1%) 289 0.82515 1 0.32334 1 0.30173 1 NA NA 1 1 1 1 0.087133 1 0.18894 1 1 1 DSCR6 3 (1%) 290 0.87841 1 0.82798 1 0.27848 1 NA NA 0.71834 1 1 1 0.34955 1 0.69398 1 1 1 RALGAPA1 7 (2%) 286 0.90885 1 0.71012 1 0.42796 1 NA NA 0.080862 1 1 1 1 1 0.058754 1 1 1 KRTAP4-9 3 (1%) 290 0.47326 1 0.54456 1 1 1 NA NA 0.37387 1 1 1 1 1 0.81142 1 1 1 COL4A5 7 (2%) 286 0.11387 1 0.64061 1 0.05222 1 NA NA 0.35071 1 0.014939 1 1 1 0.46993 1 1 1 POLR3B 4 (1%) 289 0.89646 1 0.57687 1 0.61241 1 NA NA 0.79604 1 0.14549 1 1 1 0.58946 1 1 1 EMR3 6 (2%) 287 0.63093 1 0.058712 1 1 1 NA NA 0.11682 1 1 1 0.57895 1 0.11229 1 1 1 BZW2 3 (1%) 290 0.90346 1 0.77302 1 0.27848 1 NA NA 0.24366 1 1 1 1 1 0.5832 1 1 1 OMD 3 (1%) 290 0.013518 1 0.045825 1 1 1 NA NA 0.091728 1 0.14549 1 0.34955 1 0.039275 1 1 1 PCDH10 6 (2%) 287 0.68502 1 0.16646 1 0.66842 1 NA NA 0.73163 1 1 1 0.57895 1 1 1 1 1