Clinical Features Time to Death AGE HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NEOADJUVANT.THERAPY nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p35.2) 39 (9%) 383 0.60554 1 0.00020457 0.0732 7.1881e-11 3.08e-08 1 1 0.04943 1 Amp Peak 2(1p34.3) 42 (10%) 380 0.43177 1 0.0031379 1 8.7165e-15 3.94e-12 0.37949 1 0.038753 1 Amp Peak 3(1p22.3) 68 (16%) 354 0.93812 1 0.0036265 1 0.015767 1 0.88629 1 0.28438 1 Amp Peak 4(1q21.3) 182 (43%) 240 0.26519 1 4.1957e-05 0.0156 0.0039803 1 0.67101 1 0.20985 1 Amp Peak 5(1q22) 194 (46%) 228 0.053609 1 1.9196e-06 0.000751 0.00043484 0.148 0.52737 1 0.90991 1 Amp Peak 6(1q44) 172 (41%) 250 0.3062 1 0.011624 1 0.21929 1 0.66871 1 0.64602 1 Amp Peak 7(2p23.2) 92 (22%) 330 0.0048183 1 0.0035355 1 5.2341e-10 2.23e-07 0.030591 1 0.27358 1 Amp Peak 8(2q13) 86 (20%) 336 0.012918 1 0.00035198 0.121 1.7634e-13 7.86e-11 0.69697 1 0.067981 1 Amp Peak 9(3p25.1) 59 (14%) 363 0.34925 1 0.00029191 0.102 9.1791e-09 3.8e-06 0.12922 1 0.62757 1 Amp Peak 10(3q26.2) 123 (29%) 299 0.22356 1 2.4291e-09 1.02e-06 1.1087e-22 5.28e-20 0.16589 1 0.0011415 0.385 Amp Peak 11(4p16.3) 38 (9%) 384 0.90063 1 1.4412e-06 0.000566 8.1294e-16 3.72e-13 0.71377 1 0.03105 1 Amp Peak 12(5p15.33) 61 (14%) 361 0.044682 1 0.0015943 0.531 2.6827e-15 1.22e-12 0.65422 1 0.20251 1 Amp Peak 13(6p24.2) 79 (19%) 343 0.91604 1 7.0208e-06 0.0027 5.7295e-17 2.64e-14 0.28042 1 0.11328 1 Amp Peak 14(6q25.1) 59 (14%) 363 0.5354 1 0.042832 1 0.00035056 0.121 0.76278 1 0.41894 1 Amp Peak 15(7q32.2) 57 (14%) 365 3.9759e-05 0.0148 0.3133 1 0.15157 1 0.045071 1 0.86891 1 Amp Peak 16(8p11.21) 122 (29%) 300 4.3362e-05 0.016 0.35374 1 1.2954e-06 0.00051 0.048224 1 0.26196 1 Amp Peak 17(8q24.21) 148 (35%) 274 0.0020994 0.684 0.45499 1 4.1119e-11 1.78e-08 0.09797 1 0.0019937 0.66 Amp Peak 18(8q24.21) 157 (37%) 265 0.010526 1 0.24885 1 1.0356e-11 4.52e-09 0.022212 1 0.010063 1 Amp Peak 19(9p24.2) 46 (11%) 376 0.90843 1 0.012113 1 6.8018e-07 0.00027 0.17781 1 0.046758 1 Amp Peak 20(9q34.3) 31 (7%) 391 0.075761 1 0.00039399 0.134 1.8307e-06 0.000718 0.84303 1 0.19155 1 Amp Peak 21(10q22.2) 114 (27%) 308 0.24177 1 0.52748 1 0.23279 1 0.47765 1 0.097748 1 Amp Peak 22(11p11.2) 36 (9%) 386 0.032974 1 0.00017045 0.0612 8.6169e-08 3.47e-05 0.45768 1 0.41938 1 Amp Peak 23(11q13.2) 53 (13%) 369 0.2036 1 0.0034878 1 1.0124e-06 0.000401 1 1 0.059388 1 Amp Peak 24(11q13.3) 41 (10%) 381 0.095179 1 0.15195 1 0.11514 1 0.37866 1 0.70618 1 Amp Peak 25(12p12.1) 65 (15%) 357 0.70583 1 0.57892 1 3.9305e-06 0.00152 0.38533 1 1 1 Amp Peak 26(12q13.11) 65 (15%) 357 0.82733 1 0.80321 1 2.9355e-06 0.00114 0.14653 1 0.63912 1 Amp Peak 27(12q13.2) 68 (16%) 354 0.81447 1 0.1637 1 1.0549e-05 0.00402 0.087157 1 0.75878 1 Amp Peak 28(13q34) 40 (9%) 382 0.677 1 4.5372e-07 0.000181 7.0748e-11 3.04e-08 1 1 0.24784 1 Amp Peak 29(14q24.3) 46 (11%) 376 0.4774 1 1.542e-05 0.00584 5.6024e-10 2.38e-07 0.17781 1 0.010115 1 Amp Peak 30(14q32.33) 56 (13%) 366 0.16742 1 0.0002385 0.0842 2.181e-08 9.01e-06 0.12037 1 0.020103 1 Amp Peak 31(15q26.3) 26 (6%) 396 0.83716 1 0.20178 1 0.011913 1 0.082803 1 0.10201 1 Amp Peak 32(16p11.2) 44 (10%) 378 0.19263 1 0.00038954 0.133 7.5031e-14 3.38e-11 1 1 0.0001341 0.0484 Amp Peak 33(17p13.3) 31 (7%) 391 0.46745 1 0.021312 1 2.2989e-09 9.66e-07 0.84303 1 0.009045 1 Amp Peak 34(17q11.2) 52 (12%) 370 0.052681 1 0.00023089 0.0817 2.6056e-14 1.18e-11 0.527 1 0.039566 1 Amp Peak 35(17q12) 51 (12%) 371 0.060221 1 0.00012777 0.0464 8.7774e-18 4.06e-15 0.74746 1 0.0053154 1 Amp Peak 36(17q21.32) 46 (11%) 376 0.052099 1 3.6275e-06 0.0014 1.0567e-09 4.47e-07 0.86618 1 0.046758 1 Amp Peak 37(17q25.3) 62 (15%) 360 0.11572 1 0.00031552 0.109 5.5915e-13 2.49e-10 0.65608 1 0.0012315 0.413 Amp Peak 38(18q11.2) 47 (11%) 375 0.11099 1 0.017978 1 1.9764e-11 8.58e-09 0.73824 1 1 1 Amp Peak 39(19p13.2) 66 (16%) 356 0.93554 1 4.3164e-11 1.86e-08 2.0164e-18 9.38e-16 0.24631 1 0.64103 1 Amp Peak 40(19p13.11) 64 (15%) 358 0.54706 1 1.3783e-09 5.82e-07 6.9065e-20 3.25e-17 0.30529 1 0.1152 1 Amp Peak 41(19q12) 77 (18%) 345 0.005046 1 1.6989e-09 7.15e-07 4.1032e-36 1.99e-33 0.68343 1 0.00036774 0.126 Amp Peak 42(20p13) 81 (19%) 341 0.1562 1 3.181e-05 0.0119 4.7415e-12 2.08e-09 0.18371 1 0.0061072 1 Amp Peak 43(20q11.21) 99 (23%) 323 0.073635 1 1.3032e-07 5.24e-05 2.5025e-24 1.2e-21 0.062588 1 0.015936 1 Amp Peak 44(20q13.33) 107 (25%) 315 0.36868 1 3.7452e-08 1.53e-05 7.4787e-20 3.51e-17 0.0035538 1 0.027824 1 Amp Peak 45(22q12.2) 41 (10%) 381 0.59283 1 0.002987 0.962 4.2728e-19 2e-16 0.21627 1 0.25925 1 Amp Peak 46(Xp11.22) 67 (16%) 355 0.27167 1 0.39823 1 0.12198 1 0.11329 1 0.28246 1 Amp Peak 47(Xq28) 71 (17%) 351 0.0084168 1 0.18668 1 0.027681 1 1 1 0.6523 1 Del Peak 1(1p36.21) 51 (12%) 371 0.3929 1 0.00014157 0.051 4.7056e-08 1.91e-05 0.51952 1 0.036362 1 Del Peak 2(1p36.11) 55 (13%) 367 0.29987 1 0.00025424 0.0892 6.9884e-11 3.01e-08 0.87594 1 0.091946 1 Del Peak 3(1q43) 7 (2%) 415 0.026211 1 0.020393 1 0.7451 1 0.10469 1 1 1 Del Peak 4(2p25.3) 21 (5%) 401 0.026756 1 0.13603 1 0.024032 1 0.096439 1 0.311 1 Del Peak 5(2q22.1) 33 (8%) 389 2.2092e-07 8.86e-05 0.012865 1 4.0712e-05 0.0151 0.017243 1 1 1 Del Peak 6(2q37.3) 34 (8%) 388 0.8737 1 0.00022674 0.0805 0.02703 1 0.69949 1 0.3003 1 Del Peak 7(3p14.2) 55 (13%) 367 0.77593 1 1.0886e-05 0.00414 9.0297e-14 4.05e-11 0.4346 1 0.17833 1 Del Peak 8(4p16.3) 59 (14%) 363 0.25558 1 0.00061783 0.209 4.4961e-12 1.98e-09 0.54579 1 0.021751 1 Del Peak 9(4q22.1) 71 (17%) 351 0.01787 1 7.0402e-05 0.0258 3.3755e-24 1.61e-21 0.20515 1 0.0023909 0.777 Del Peak 10(4q34.3) 86 (20%) 336 0.050942 1 0.00012781 0.0464 1.3231e-24 6.35e-22 0.36295 1 7.213e-05 0.0264 Del Peak 11(5q11.2) 69 (16%) 353 0.12244 1 2.2584e-05 0.00849 1.5048e-22 7.15e-20 0.77651 1 0.046057 1 Del Peak 12(6q26) 33 (8%) 389 0.21371 1 0.016233 1 3.8688e-08 1.58e-05 0.84489 1 0.40801 1 Del Peak 13(7p22.3) 53 (13%) 369 0.034317 1 1.9811e-05 0.00747 1.6414e-12 7.27e-10 0.75142 1 0.025721 1 Del Peak 14(7q31.1) 38 (9%) 384 0.70623 1 3.406e-06 0.00132 5.9315e-17 2.72e-14 0.71377 1 0.0013572 0.453 Del Peak 15(7q36.3) 48 (11%) 374 0.56588 1 4.2614e-08 1.73e-05 1.2192e-16 5.58e-14 1 1 0.019397 1 Del Peak 16(8p23.2) 77 (18%) 345 0.29457 1 0.002038 0.668 2.6788e-25 1.29e-22 0.68343 1 0.002007 0.662 Del Peak 17(8p21.2) 77 (18%) 345 0.62466 1 4.2327e-05 0.0157 1.4313e-32 6.91e-30 0.68343 1 0.00011043 0.0403 Del Peak 18(9p23) 46 (11%) 376 0.37175 1 0.00026679 0.0931 1.4819e-10 6.33e-08 0.3135 1 0.20486 1 Del Peak 19(9q21.2) 88 (21%) 334 0.076496 1 7.0081e-12 3.07e-09 1.6978e-19 7.95e-17 0.30111 1 0.025909 1 Del Peak 20(9q34.11) 95 (23%) 327 0.48587 1 7.6997e-10 3.26e-07 4.0247e-18 1.86e-15 0.31359 1 0.014432 1 Del Peak 21(10p12.31) 27 (6%) 395 0.67175 1 0.16526 1 2.9406e-05 0.011 0.39205 1 0.062274 1 Del Peak 22(10q21.1) 27 (6%) 395 0.91252 1 0.064568 1 0.007045 1 1 1 0.82088 1 Del Peak 23(10q23.31) 50 (12%) 372 0.23894 1 0.030099 1 0.00022116 0.079 0.075529 1 0.38249 1 Del Peak 24(11p15.5) 72 (17%) 350 0.023448 1 6.9538e-08 2.81e-05 2.4231e-21 1.15e-18 0.16199 1 0.016334 1 Del Peak 25(11q14.1) 48 (11%) 374 0.048467 1 9.6024e-06 0.00368 3.2033e-12 1.42e-09 0.62033 1 0.019397 1 Del Peak 26(11q25) 67 (16%) 355 0.0028703 0.927 0.00012411 0.0452 1.0576e-13 4.74e-11 0.030174 1 0.06251 1 Del Peak 27(12q23.1) 31 (7%) 391 0.0455 1 0.0045125 1 2.2989e-09 9.66e-07 0.68699 1 0.009045 1 Del Peak 28(12q24.33) 40 (9%) 382 0.074096 1 0.00022117 0.079 1.5492e-11 6.74e-09 0.1499 1 0.03196 1 Del Peak 29(13q14.2) 64 (15%) 358 0.075669 1 0.0020698 0.677 0.00025256 0.0889 0.18689 1 0.75296 1 Del Peak 30(14q13.1) 51 (12%) 371 0.0038641 1 0.0050503 1 3.6561e-12 1.61e-09 0.63001 1 0.081556 1 Del Peak 31(15q15.1) 95 (23%) 327 0.061342 1 3.8425e-09 1.6e-06 8.2957e-20 3.89e-17 0.060257 1 0.014432 1 Del Peak 32(15q23) 76 (18%) 346 0.048439 1 1.2785e-06 0.000505 5.2909e-19 2.47e-16 0.22128 1 0.039453 1 Del Peak 33(16p13.3) 59 (14%) 363 0.02858 1 2.8562e-08 1.17e-05 2.3039e-15 1.05e-12 0.36432 1 0.41894 1 Del Peak 34(16q21) 108 (26%) 314 0.086491 1 2.9232e-09 1.22e-06 7.2109e-21 3.4e-18 0.33479 1 0.0043164 1 Del Peak 35(16q22.3) 113 (27%) 309 0.14002 1 6.4984e-09 2.7e-06 1.532e-21 7.26e-19 0.47904 1 0.010999 1 Del Peak 36(16q23.1) 118 (28%) 304 0.10149 1 3.2962e-08 1.35e-05 2.2279e-24 1.07e-21 0.41437 1 0.00025547 0.0894 Del Peak 37(17p13.3) 77 (18%) 345 0.20858 1 3.3725e-06 0.00131 2.1325e-18 9.89e-16 0.3408 1 0.002007 0.662 Del Peak 38(17p11.2) 83 (20%) 339 0.086211 1 2.5636e-08 1.06e-05 4.3644e-26 2.1e-23 0.35581 1 0.001659 0.551 Del Peak 39(17q11.2) 70 (17%) 352 0.83493 1 6.4338e-07 0.000256 9.6483e-12 4.22e-09 0.20453 1 0.17154 1 Del Peak 40(17q21.31) 67 (16%) 355 0.60329 1 5.1665e-06 0.00199 7.5202e-11 3.22e-08 0.31504 1 0.06251 1 Del Peak 41(18q23) 68 (16%) 354 0.02839 1 0.00031214 0.108 7.3718e-15 3.34e-12 0.0039324 1 0.53902 1 Del Peak 42(19p13.3) 106 (25%) 316 0.0077973 1 1.2676e-13 5.67e-11 1.6424e-41 7.97e-39 0.27514 1 0.00063264 0.214 Del Peak 43(19p12) 34 (8%) 388 0.090704 1 0.0027147 0.88 2.4012e-07 9.6e-05 0.24516 1 0.3003 1 Del Peak 44(19q13.43) 44 (10%) 378 0.0011883 0.399 1.8861e-05 0.00713 4.8597e-15 2.21e-12 0.86533 1 0.01493 1 Del Peak 45(20p12.1) 23 (5%) 399 0.2332 1 0.056197 1 0.029482 1 0.65125 1 0.80791 1 Del Peak 46(20q13.12) 10 (2%) 412 0.95578 1 0.53277 1 0.074172 1 0.076452 1 0.71326 1 Del Peak 47(22q11.21) 54 (13%) 368 0.75006 1 0.0090244 1 0.022556 1 0.039872 1 0.3981 1 Del Peak 48(22q12.1) 65 (15%) 357 0.37442 1 0.0030496 0.979 1.0531e-05 0.00402 0.080767 1 0.12075 1 Del Peak 49(22q13.31) 92 (22%) 330 0.032912 1 5.4567e-08 2.21e-05 4.2358e-17 1.95e-14 0.30792 1 0.028363 1 Del Peak 50(Xp21.1) 60 (14%) 362 0.0032003 1 5.6446e-05 0.0208 6.5537e-13 2.91e-10 0.45611 1 0.51788 1