Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.004 0.127 -9999.0 0.0 -0.286 6.0 6.0 MAP3K8 -0.011 0.103 -9999.0 0.0 -0.355 4.0 4.0 FOS -0.001 0.089 -9999.0 0.0 -0.295 1.0 1.0 PRKCA 0.008 0.075 -9999.0 0.0 -0.357 2.0 2.0 PTPN7 0.019 0.02 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.028 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.005 -9999.0 0.0 -0.015 7.0 7.0 NRAS 0.027 0.014 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.046 0.025 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.009 0.072 -9999.0 0.0 -0.4 1.0 1.0 MAP2K1 -0.017 0.08 -9999.0 0.0 -0.256 4.0 4.0 ELK1 0.022 0.023 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.003 0.062 -9999.0 0.0 -0.308 2.0 2.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 7.0 7.0 MAPK1 0.008 0.083 -9999.0 0.0 -0.499 1.0 1.0 RAF1 0.002 0.048 -9999.0 0.0 -0.33 1.0 1.0 KRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0