Clinical Features Time to Death AGE HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NEOADJUVANT.THERAPY nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p35.2) 40 (9%) 403 0.95946 1 0.00012377 0.0443 3.3322e-10 1.42e-07 1 1 0.04901 1 Amp Peak 2(1p34.2) 50 (11%) 393 0.57437 1 0.00013255 0.0473 3.5687e-16 1.64e-13 0.41293 1 0.03488 1 Amp Peak 3(1p22.3) 73 (16%) 370 0.70156 1 0.00057306 0.192 0.0094306 1 0.88915 1 0.22937 1 Amp Peak 4(1q21.3) 192 (43%) 251 0.16494 1 3.5509e-06 0.00138 0.0043132 1 0.60226 1 0.17595 1 Amp Peak 5(1q22) 204 (46%) 239 0.036696 1 1.6501e-07 6.72e-05 0.0002327 0.08 0.53342 1 0.82284 1 Amp Peak 6(1q42.3) 182 (41%) 261 0.25577 1 0.0011283 0.369 0.18233 1 0.59971 1 0.6512 1 Amp Peak 7(2p23.2) 93 (21%) 350 0.0056213 1 0.0026259 0.827 2.2066e-10 9.47e-08 0.055714 1 0.1733 1 Amp Peak 8(2q13) 88 (20%) 355 0.015043 1 0.00016319 0.0571 1.0017e-14 4.54e-12 0.79536 1 0.05059 1 Amp Peak 9(3p25.1) 60 (14%) 383 0.36795 1 0.00018841 0.0658 2.5682e-09 1.08e-06 0.17208 1 0.62425 1 Amp Peak 10(3p14.1) 48 (11%) 395 0.0042856 1 0.0088134 1 0.0037635 1 0.044069 1 1 1 Amp Peak 11(3q26.2) 128 (29%) 315 0.14279 1 3.511e-09 1.48e-06 6.1748e-22 2.96e-19 0.16989 1 0.0012597 0.409 Amp Peak 12(3q26.2) 121 (27%) 322 0.081507 1 3.656e-07 0.000147 1.0282e-22 4.95e-20 0.24522 1 0.0057653 1 Amp Peak 13(4p16.3) 39 (9%) 404 0.91601 1 1.7395e-06 0.000684 5.8942e-15 2.68e-12 0.71469 1 0.029846 1 Amp Peak 14(5p15.33) 64 (14%) 379 0.050969 1 0.0052911 1 2.61e-16 1.2e-13 0.55835 1 0.26529 1 Amp Peak 15(5q35.3) 39 (9%) 404 0.11043 1 0.00048875 0.165 3.2078e-07 0.000129 0.36538 1 0.55385 1 Amp Peak 16(6p24.2) 83 (19%) 360 0.84388 1 9.7783e-07 0.000387 1.6072e-17 7.52e-15 0.23191 1 0.15167 1 Amp Peak 17(6q25.1) 64 (14%) 379 0.81804 1 0.0091926 1 0.00016109 0.0567 0.55835 1 0.63352 1 Amp Peak 18(7q22.1) 69 (16%) 374 0.00049216 0.166 0.036077 1 0.043704 1 0.11654 1 1 1 Amp Peak 19(8p11.21) 130 (29%) 313 1.6147e-05 0.00615 0.46606 1 1.2254e-06 0.000483 0.041131 1 0.22054 1 Amp Peak 20(8q24.21) 161 (36%) 282 0.0010651 0.35 0.59417 1 5.8517e-11 2.53e-08 0.052283 1 0.0036236 1 Amp Peak 21(8q24.21) 169 (38%) 274 0.0057554 1 0.26266 1 1.0982e-11 4.79e-09 0.014038 1 0.015492 1 Amp Peak 22(9p24.2) 48 (11%) 395 0.75282 1 0.0052761 1 3.9037e-07 0.000156 0.18178 1 0.049069 1 Amp Peak 23(9q34.3) 31 (7%) 412 0.081586 1 0.00050804 0.171 2.2615e-06 0.000887 0.83938 1 0.12539 1 Amp Peak 24(10q22.2) 121 (27%) 322 0.19797 1 0.43077 1 0.18037 1 0.64242 1 0.044643 1 Amp Peak 25(11p11.2) 37 (8%) 406 0.037562 1 0.00022005 0.0761 2.9141e-07 0.000118 0.85155 1 0.22464 1 Amp Peak 26(11q13.2) 56 (13%) 387 0.096749 1 0.0010685 0.35 1.0739e-06 0.000424 1 1 0.028955 1 Amp Peak 27(12p12.1) 67 (15%) 376 0.75591 1 0.49016 1 2.2922e-06 0.000896 0.66442 1 1 1 Amp Peak 28(12q13.11) 66 (15%) 377 0.80416 1 0.85466 1 6.595e-06 0.00255 0.1907 1 0.75372 1 Amp Peak 29(12q13.2) 74 (17%) 369 0.90772 1 0.070657 1 7.5349e-06 0.00291 0.051523 1 0.88167 1 Amp Peak 30(13q34) 40 (9%) 403 0.66458 1 7.0022e-07 0.000278 9.9108e-11 4.27e-08 1 1 0.17551 1 Amp Peak 31(14q24.3) 48 (11%) 395 0.50448 1 1.7757e-05 0.00675 2.5018e-11 1.09e-08 0.18178 1 0.010824 1 Amp Peak 32(14q32.33) 57 (13%) 386 0.18202 1 0.00021072 0.0731 6.7588e-09 2.84e-06 0.12378 1 0.018592 1 Amp Peak 33(16p11.2) 46 (10%) 397 0.081422 1 0.00013685 0.0486 5.299e-14 2.37e-11 1 1 0.00016219 0.0569 Amp Peak 34(17q11.2) 52 (12%) 391 0.046092 1 0.00022116 0.0763 6.602e-17 3.06e-14 0.74756 1 0.024596 1 Amp Peak 35(17q12) 53 (12%) 390 0.06493 1 5.9946e-05 0.0221 7.2922e-18 3.43e-15 0.75039 1 0.0056253 1 Amp Peak 36(17q25.1) 74 (17%) 369 0.044311 1 5.7275e-05 0.0211 8.6286e-16 3.95e-13 1 1 0.0067402 1 Amp Peak 37(18p11.31) 66 (15%) 377 0.48751 1 0.000145 0.0512 1.6652e-18 7.86e-16 0.057806 1 0.87662 1 Amp Peak 38(18q11.2) 49 (11%) 394 0.11876 1 0.012992 1 6.5543e-13 2.9e-10 0.62372 1 1 1 Amp Peak 39(19p13.2) 69 (16%) 374 0.66519 1 3.8097e-11 1.65e-08 6.7191e-18 3.16e-15 0.19996 1 0.64447 1 Amp Peak 40(19p13.11) 68 (15%) 375 0.60734 1 1.1472e-10 4.93e-08 3.1441e-20 1.5e-17 0.083675 1 0.53925 1 Amp Peak 41(19q12) 80 (18%) 363 0.0019336 0.615 2.8046e-10 1.2e-07 8.4347e-37 4.12e-34 0.68628 1 0.00040487 0.137 Amp Peak 42(20p13) 86 (19%) 357 0.1746 1 9.498e-05 0.0343 2.524e-12 1.11e-09 0.23893 1 0.0044323 1 Amp Peak 43(20q11.21) 106 (24%) 337 0.03894 1 1.5303e-07 6.24e-05 1.6459e-23 7.95e-21 0.068165 1 0.012647 1 Amp Peak 44(20q13.12) 111 (25%) 332 0.30368 1 4.4071e-08 1.81e-05 1.8012e-19 8.54e-17 0.016433 1 0.0095636 1 Amp Peak 45(20q13.33) 109 (25%) 334 0.33276 1 1.7192e-07 6.98e-05 2.4479e-15 1.12e-12 0.0054509 1 0.019884 1 Amp Peak 46(22q12.2) 41 (9%) 402 0.60569 1 0.0037359 1 7.2143e-19 3.41e-16 0.28516 1 0.24615 1 Amp Peak 47(Xp11.23) 71 (16%) 372 0.43215 1 0.31049 1 0.090008 1 0.0473 1 0.22354 1 Amp Peak 48(Xq28) 72 (16%) 371 0.0089847 1 0.10078 1 0.0059079 1 1 1 1 1 Del Peak 1(1p36.21) 53 (12%) 390 0.412 1 6.5702e-05 0.0241 3.1265e-08 1.29e-05 0.52461 1 0.037593 1 Del Peak 2(1p36.11) 58 (13%) 385 0.32115 1 7.2754e-05 0.0266 8.4392e-12 3.7e-09 0.75931 1 0.097182 1 Del Peak 3(1q43) 7 (2%) 436 0.028443 1 0.021671 1 0.75017 1 0.10835 1 1 1 Del Peak 4(2p25.3) 22 (5%) 421 0.027603 1 0.11811 1 0.041951 1 0.098115 1 0.31361 1 Del Peak 5(2q22.1) 34 (8%) 409 1.0997e-08 4.6e-06 0.0077214 1 9.5072e-05 0.0343 0.018054 1 1 1 Del Peak 6(2q37.3) 38 (9%) 405 0.48364 1 0.00070621 0.234 0.037369 1 0.46056 1 0.42805 1 Del Peak 7(3p14.2) 56 (13%) 387 0.79685 1 2.7572e-05 0.0103 2.5762e-14 1.16e-11 0.4375 1 0.12991 1 Del Peak 8(3q13.31) 21 (5%) 422 0.92001 1 0.0032128 1 3.179e-05 0.0119 0.63124 1 0.2967 1 Del Peak 9(4p16.3) 65 (15%) 378 0.13881 1 6.8749e-05 0.0252 6.1666e-13 2.73e-10 0.55821 1 0.026011 1 Del Peak 10(4p15.31) 64 (14%) 379 0.13656 1 9.3036e-05 0.0337 8.5411e-12 3.73e-09 0.14144 1 0.42656 1 Del Peak 11(4q22.1) 76 (17%) 367 0.0076295 1 1.3134e-05 0.00503 5.3364e-24 2.59e-21 0.21659 1 0.0017792 0.568 Del Peak 12(4q34.3) 90 (20%) 353 0.024781 1 2.1273e-05 0.00804 1.4312e-23 6.93e-21 0.51968 1 4.2e-05 0.0156 Del Peak 13(5q11.2) 76 (17%) 367 0.061494 1 7.577e-05 0.0276 5.7522e-23 2.77e-20 0.6812 1 0.053057 1 Del Peak 14(6q26) 34 (8%) 409 0.22368 1 0.0092882 1 8.6336e-09 3.62e-06 0.84577 1 0.40616 1 Del Peak 15(7p22.3) 56 (13%) 387 0.010055 1 2.6213e-05 0.00986 2.1795e-13 9.7e-11 0.64169 1 0.064251 1 Del Peak 16(7q11.22) 31 (7%) 412 0.55002 1 1.9077e-05 0.00723 3.1673e-07 0.000128 0.68777 1 0.049525 1 Del Peak 17(7q31.1) 39 (9%) 404 0.69561 1 3.2439e-06 0.00127 1.0067e-17 4.72e-15 0.71469 1 0.0012774 0.414 Del Peak 18(7q36.3) 49 (11%) 394 0.58165 1 3.5282e-08 1.45e-05 2.7625e-17 1.28e-14 1 1 0.012202 1 Del Peak 19(8p23.2) 79 (18%) 364 0.3117 1 0.0029361 0.922 2.7201e-25 1.33e-22 0.68648 1 0.0019496 0.618 Del Peak 20(9p23) 50 (11%) 393 0.39706 1 0.00037902 0.129 6.7502e-10 2.86e-07 0.41293 1 0.15828 1 Del Peak 21(9q34.11) 101 (23%) 342 0.31876 1 2.5546e-10 1.09e-07 1.1781e-16 5.45e-14 0.32382 1 0.011 1 Del Peak 22(10q23.31) 52 (12%) 391 0.10801 1 0.0141 1 0.00013652 0.0486 0.077533 1 0.3857 1 Del Peak 23(11p15.5) 76 (17%) 367 0.0087147 1 2.8076e-08 1.16e-05 1.0254e-21 4.91e-19 0.13047 1 0.025469 1 Del Peak 24(11q14.1) 50 (11%) 393 0.052023 1 1.0392e-05 0.00399 1.7331e-13 7.73e-11 0.62359 1 0.020355 1 Del Peak 25(11q25) 68 (15%) 375 0.0033843 1 8.4132e-05 0.0305 3.1932e-14 1.44e-11 0.04327 1 0.043126 1 Del Peak 26(12q23.1) 33 (7%) 410 0.048446 1 0.0031906 0.999 5.4546e-11 2.36e-08 0.55561 1 0.017114 1 Del Peak 27(12q24.33) 43 (10%) 400 0.08122 1 0.00011294 0.0405 4.7877e-14 2.15e-11 0.11395 1 0.03711 1 Del Peak 28(13q11) 67 (15%) 376 0.01225 1 0.00094696 0.312 1.1103e-09 4.7e-07 0.25095 1 0.21323 1 Del Peak 29(13q14.2) 71 (16%) 372 0.03401 1 0.00060559 0.202 0.00030605 0.105 0.15794 1 0.76098 1 Del Peak 30(14q13.1) 54 (12%) 389 0.00090874 0.301 0.0013943 0.45 8.1761e-12 3.59e-09 0.52994 1 0.087679 1 Del Peak 31(15q15.1) 102 (23%) 341 0.031755 1 1.5392e-08 6.4e-06 2.672e-20 1.27e-17 0.065359 1 0.011594 1 Del Peak 32(15q23) 82 (19%) 361 0.056198 1 8.7254e-06 0.00336 6.7529e-20 3.21e-17 0.23269 1 0.043131 1 Del Peak 33(16p13.3) 61 (14%) 382 0.032498 1 2.7397e-08 1.13e-05 1.7674e-15 8.08e-13 0.54925 1 0.25857 1 Del Peak 34(16q21) 116 (26%) 327 0.047946 1 1.5149e-08 6.32e-06 4.2726e-21 2.04e-18 0.28931 1 0.0049907 1 Del Peak 35(16q23.1) 126 (28%) 317 0.059099 1 1.0011e-07 4.09e-05 1.1917e-24 5.79e-22 0.42202 1 0.00029953 0.103 Del Peak 36(17p13.3) 84 (19%) 359 0.11515 1 4.0906e-05 0.0152 3.1071e-16 1.43e-13 0.29212 1 0.0025746 0.814 Del Peak 37(17p12) 96 (22%) 347 0.069242 1 3.0885e-07 0.000125 1.1222e-24 5.47e-22 0.53042 1 0.00062183 0.207 Del Peak 38(17p11.2) 87 (20%) 356 0.038788 1 3.6291e-06 0.00141 1.969e-17 9.2e-15 0.43729 1 0.090809 1 Del Peak 39(17q11.2) 77 (17%) 366 0.5811 1 1.6013e-05 0.00612 3.0452e-10 1.3e-07 0.17386 1 0.18438 1 Del Peak 40(17q21.2) 82 (19%) 361 0.12963 1 2.1297e-05 0.00804 5.0831e-14 2.28e-11 0.14404 1 0.11518 1 Del Peak 41(18q23) 73 (16%) 370 0.011765 1 0.0017097 0.547 6.409e-15 2.91e-12 0.0050914 1 0.45179 1 Del Peak 42(19p13.3) 115 (26%) 328 0.013305 1 5.2956e-12 2.33e-09 1.2302e-44 6.03e-42 0.34424 1 0.00031977 0.109 Del Peak 43(19p12) 37 (8%) 406 0.10045 1 0.04837 1 5.1611e-07 0.000205 0.2681 1 0.22464 1 Del Peak 44(19q13.43) 47 (11%) 396 0.001483 0.478 0.0012145 0.396 1.6322e-14 7.38e-12 1 1 0.0064153 1 Del Peak 45(20p12.1) 24 (5%) 419 0.077704 1 0.032019 1 0.050283 1 0.81912 1 0.80955 1 Del Peak 46(22q11.1) 65 (15%) 378 0.40504 1 4.6335e-05 0.0171 0.00019542 0.068 0.028268 1 0.6366 1 Del Peak 47(22q12.1) 70 (16%) 373 0.20609 1 0.0015057 0.483 3.7769e-05 0.0141 0.090439 1 0.12457 1 Del Peak 48(22q13.31) 99 (22%) 344 0.015627 1 1.7823e-08 7.4e-06 1.7467e-16 8.07e-14 0.26434 1 0.031256 1 Del Peak 49(22q13.32) 105 (24%) 338 0.014074 1 4.0986e-07 0.000164 2.4984e-17 1.16e-14 0.068809 1 0.066755 1 Del Peak 50(Xp21.1) 62 (14%) 381 0.0038567 1 0.00013679 0.0486 4.1866e-13 1.86e-10 0.5502 1 0.51934 1