Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.095 0.204 0.455 22.0 -9999.0 0.0 22.0 KIRREL -0.091 0.232 -9999.0 0.0 -0.63 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.095 0.204 -9999.0 0.0 -0.456 22.0 22.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.077 0.148 -9999.0 0.0 -0.404 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.035 0.121 -9999.0 0.0 -0.323 12.0 12.0 FYN -0.063 0.147 -9999.0 0.0 -0.362 14.0 14.0 mol:Ca2+ -0.076 0.146 -9999.0 0.0 -0.4 12.0 12.0 mol:DAG -0.076 0.147 -9999.0 0.0 -0.402 12.0 12.0 NPHS2 -0.012 0.025 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.076 0.147 -9999.0 0.0 -0.402 12.0 12.0 regulation of endocytosis -0.052 0.139 -9999.0 0.0 -0.355 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.079 0.151 -9999.0 0.0 -0.341 22.0 22.0 establishment of cell polarity -0.095 0.204 -9999.0 0.0 -0.455 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 -0.059 0.139 -9999.0 0.0 -0.365 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.052 0.141 -9999.0 0.0 -0.36 12.0 12.0 NPHS1 -0.051 0.152 -9999.0 0.0 -0.521 9.0 9.0 Nephrin/NEPH1/podocin -0.064 0.147 -9999.0 0.0 -0.364 14.0 14.0 TJP1 0.006 0.067 -9999.0 0.0 -0.65 1.0 1.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.077 0.148 -9999.0 0.0 -0.404 12.0 12.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.077 0.148 -9999.0 0.0 -0.404 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.082 0.163 -9999.0 0.0 -0.357 20.0 20.0 cytoskeleton organization -0.041 0.145 -9999.0 0.0 -0.38 12.0 12.0 Nephrin/NEPH1 -0.067 0.15 -9999.0 0.0 -0.329 22.0 22.0 Nephrin/NEPH1/ZO-1 -0.087 0.163 -9999.0 0.0 -0.434 13.0 13.0