Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.04 0.161 0.432 12.0 -9999.0 0.0 12.0 KIRREL -0.061 0.204 -9999.0 0.0 -0.506 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.04 0.161 -9999.0 0.0 -0.433 12.0 12.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.017 0.127 -9999.0 0.0 -0.341 11.0 11.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.098 -9999.0 0.0 -0.284 11.0 11.0 FYN -0.027 0.118 -9999.0 0.0 -0.319 11.0 11.0 mol:Ca2+ -0.012 0.123 -9999.0 0.0 -0.339 10.0 10.0 mol:DAG -0.012 0.124 -9999.0 0.0 -0.34 10.0 10.0 NPHS2 -0.009 0.019 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.012 0.124 -9999.0 0.0 -0.34 10.0 10.0 regulation of endocytosis -0.014 0.114 -9999.0 0.0 -0.302 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.026 0.122 -9999.0 0.0 -0.339 11.0 11.0 establishment of cell polarity -0.04 0.161 -9999.0 0.0 -0.432 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 -0.013 0.12 -9999.0 0.0 -0.314 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 -0.013 0.116 -9999.0 0.0 -0.305 11.0 11.0 NPHS1 -0.009 0.071 -9999.0 0.0 -0.23 6.0 6.0 Nephrin/NEPH1/podocin -0.025 0.115 -9999.0 0.0 -0.321 11.0 11.0 TJP1 0.021 0.062 -9999.0 0.0 -0.574 1.0 1.0 NCK1 0.021 0.012 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.011 0.125 -9999.0 0.0 -0.342 10.0 10.0 CD2AP 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.016 0.128 -9999.0 0.0 -0.341 11.0 11.0 GRB2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.037 0.126 -9999.0 0.0 -0.321 13.0 13.0 cytoskeleton organization -0.037 0.117 0.2 2.0 -0.336 11.0 13.0 Nephrin/NEPH1 -0.024 0.116 -9999.0 0.0 -0.308 12.0 12.0 Nephrin/NEPH1/ZO-1 -0.02 0.143 -9999.0 0.0 -0.369 12.0 12.0