Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.017 0.099 0.324 18.0 -9999.0 0.0 18.0 KIRREL -0.01 0.098 -9999.0 0.0 -0.476 8.0 8.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.017 0.1 -9999.0 0.0 -0.325 18.0 18.0 PLCG1 0.005 0.059 -9999.0 0.0 -0.462 3.0 3.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.027 0.118 -9999.0 0.0 -0.317 21.0 21.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.005 0.069 -9999.0 0.0 -0.549 1.0 1.0 FYN -0.009 0.074 -9999.0 0.0 -0.256 7.0 7.0 mol:Ca2+ -0.007 0.086 -9999.0 0.0 -0.309 8.0 8.0 mol:DAG -0.006 0.087 -9999.0 0.0 -0.31 8.0 8.0 NPHS2 -0.003 0.014 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.006 0.087 -9999.0 0.0 -0.31 8.0 8.0 regulation of endocytosis 0.0 0.071 -9999.0 0.0 -0.383 1.0 1.0 Nephrin/NEPH1/podocin/Cholesterol -0.01 0.073 -9999.0 0.0 -0.233 18.0 18.0 establishment of cell polarity -0.017 0.099 -9999.0 0.0 -0.324 18.0 18.0 Nephrin/NEPH1/podocin/NCK1-2 0.003 0.078 -9999.0 0.0 -0.363 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 0.001 0.072 -9999.0 0.0 -0.388 1.0 1.0 NPHS1 -0.016 0.102 -9999.0 0.0 -0.449 10.0 10.0 Nephrin/NEPH1/podocin -0.008 0.075 -9999.0 0.0 -0.257 7.0 7.0 TJP1 0.01 0.035 -9999.0 0.0 -0.479 1.0 1.0 NCK1 0.008 0.05 -9999.0 0.0 -0.479 2.0 2.0 NCK2 0.01 0.035 -9999.0 0.0 -0.479 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.006 0.087 -9999.0 0.0 -0.311 8.0 8.0 CD2AP -0.031 0.14 -9999.0 0.0 -0.479 17.0 17.0 Nephrin/NEPH1/podocin/GRB2 -0.002 0.073 -9999.0 0.0 -0.252 6.0 6.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.018 0.095 -9999.0 0.0 -0.276 16.0 16.0 cytoskeleton organization 0.008 0.072 -9999.0 0.0 -0.466 1.0 1.0 Nephrin/NEPH1 -0.009 0.069 -9999.0 0.0 -0.223 18.0 18.0 Nephrin/NEPH1/ZO-1 -0.004 0.086 -9999.0 0.0 -0.316 6.0 6.0