Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.019 0.141 0.305 1.0 -0.579 2.0 3.0 MAP3K8 0.025 0.051 -9999.0 0.0 -0.416 1.0 1.0 FOS 0.008 0.119 0.315 1.0 -0.456 3.0 4.0 PRKCA 0.028 0.025 -9999.0 0.0 -0.111 1.0 1.0 PTPN7 0.027 0.062 -9999.0 0.0 -0.425 1.0 1.0 HRAS 0.033 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.031 0.02 -9999.0 0.0 -9999.0 0.0 0.0 NRAS 0.02 0.07 -9999.0 0.0 -0.416 2.0 2.0 RAS family/GTP 0.035 0.087 -9999.0 0.0 -0.368 3.0 3.0 MAPK3 0.024 0.092 -9999.0 0.0 -0.495 2.0 2.0 MAP2K1 0.005 0.057 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.029 0.017 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.009 0.03 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 4.0 4.0 MAPK1 -0.008 0.138 -9999.0 0.0 -0.403 8.0 8.0 RAF1 0.004 0.052 -9999.0 0.0 -0.268 2.0 2.0 KRAS 0.014 0.085 -9999.0 0.0 -0.416 3.0 3.0