Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.029 0.128 0.418 15.0 -9999.0 0.0 15.0 KIRREL -0.044 0.173 -9999.0 0.0 -0.57 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.029 0.128 -9999.0 0.0 -0.418 15.0 15.0 PLCG1 0.009 0.048 -9999.0 0.0 -0.579 1.0 1.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.011 0.096 -9999.0 0.0 -0.311 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.084 -9999.0 0.0 -0.267 13.0 13.0 FYN -0.013 0.09 -9999.0 0.0 -0.297 13.0 13.0 mol:Ca2+ -0.031 0.099 -9999.0 0.0 -0.333 13.0 13.0 mol:DAG -0.023 0.102 -9999.0 0.0 -0.335 13.0 13.0 NPHS2 -0.003 0.016 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.023 0.102 -9999.0 0.0 -0.335 13.0 13.0 regulation of endocytosis -0.005 0.085 -9999.0 0.0 -0.273 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol -0.019 0.096 -9999.0 0.0 -0.309 15.0 15.0 establishment of cell polarity -0.029 0.128 -9999.0 0.0 -0.418 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.09 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.004 0.086 -9999.0 0.0 -0.276 13.0 13.0 NPHS1 0.001 0.017 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.014 0.09 -9999.0 0.0 -0.298 13.0 13.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.041 -9999.0 0.0 -0.495 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.013 0.106 -9999.0 0.0 -0.336 13.0 13.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.011 0.096 -9999.0 0.0 -0.311 13.0 13.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.036 0.127 -9999.0 0.0 -0.316 24.0 24.0 cytoskeleton organization 0.001 0.096 -9999.0 0.0 -0.301 13.0 13.0 Nephrin/NEPH1 -0.019 0.091 -9999.0 0.0 -0.296 15.0 15.0 Nephrin/NEPH1/ZO-1 -0.013 0.104 -9999.0 0.0 -0.337 13.0 13.0