Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.015 0.094 0.283 13.0 -9999.0 0.0 13.0 KIRREL -0.001 0.121 -9999.0 0.0 -0.39 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.015 0.094 -9999.0 0.0 -0.284 13.0 13.0 PLCG1 0.028 0.035 -9999.0 0.0 -0.383 1.0 1.0 ARRB2 0.033 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.016 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.032 0.079 -9999.0 0.0 -0.209 13.0 13.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.002 0.055 -9999.0 0.0 -0.209 9.0 9.0 FYN 0.005 0.072 0.144 11.0 -0.199 13.0 24.0 mol:Ca2+ 0.028 0.083 -9999.0 0.0 -0.222 13.0 13.0 mol:DAG 0.029 0.084 -9999.0 0.0 -0.223 13.0 13.0 NPHS2 -0.005 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.029 0.084 -9999.0 0.0 -0.223 13.0 13.0 regulation of endocytosis 0.031 0.073 -9999.0 0.0 -0.192 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.017 0.071 -9999.0 0.0 -0.203 13.0 13.0 establishment of cell polarity 0.015 0.094 -9999.0 0.0 -0.283 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.049 0.081 -9999.0 0.0 -0.194 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.033 0.075 -9999.0 0.0 -0.193 13.0 13.0 NPHS1 0.021 0.026 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.015 0.068 -9999.0 0.0 -0.2 13.0 13.0 TJP1 0.034 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.034 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.034 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.03 0.085 -9999.0 0.0 -0.224 13.0 13.0 CD2AP 0.033 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.036 0.077 -9999.0 0.0 -0.209 12.0 12.0 GRB2 0.034 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.019 0.089 0.149 12.0 -0.205 21.0 33.0 cytoskeleton organization -0.015 0.058 0.197 1.0 -0.229 8.0 9.0 Nephrin/NEPH1 0.017 0.066 -9999.0 0.0 -0.192 13.0 13.0 Nephrin/NEPH1/ZO-1 0.034 0.084 -9999.0 0.0 -0.226 13.0 13.0