Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.003 0.106 0.424 15.0 -9999.0 0.0 15.0 KIRREL -0.003 0.124 -9999.0 0.0 -0.541 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.003 0.107 -9999.0 0.0 -0.425 15.0 15.0 PLCG1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.018 0.085 -9999.0 0.0 -0.316 15.0 15.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.065 -9999.0 0.0 -0.285 12.0 12.0 FYN -0.004 0.077 0.274 1.0 -0.295 16.0 17.0 mol:Ca2+ 0.017 0.084 -9999.0 0.0 -0.315 15.0 15.0 mol:DAG 0.018 0.084 -9999.0 0.0 -0.316 15.0 15.0 NPHS2 -0.006 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.018 0.084 -9999.0 0.0 -0.316 15.0 15.0 regulation of endocytosis 0.024 0.08 -9999.0 0.0 -0.279 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol 0.005 0.08 -9999.0 0.0 -0.316 15.0 15.0 establishment of cell polarity 0.003 0.106 -9999.0 0.0 -0.424 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 0.027 0.079 -9999.0 0.0 -0.294 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 0.026 0.081 -9999.0 0.0 -0.282 16.0 16.0 NPHS1 -0.013 0.059 -9999.0 0.0 -0.225 5.0 5.0 Nephrin/NEPH1/podocin 0.007 0.078 -9999.0 0.0 -0.296 16.0 16.0 TJP1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.019 0.085 -9999.0 0.0 -0.317 15.0 15.0 CD2AP 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.02 0.086 -9999.0 0.0 -0.319 15.0 15.0 GRB2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.016 0.071 -9999.0 0.0 -0.292 15.0 15.0 cytoskeleton organization -0.011 0.073 0.198 2.0 -0.321 13.0 15.0 Nephrin/NEPH1 0.007 0.076 -9999.0 0.0 -0.301 15.0 15.0 Nephrin/NEPH1/ZO-1 0.021 0.092 -9999.0 0.0 -0.343 15.0 15.0