Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.067 0.157 0.346 15.0 -9999.0 0.0 15.0 KIRREL -0.046 0.155 -9999.0 0.0 -0.49 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.067 0.158 -9999.0 0.0 -0.346 15.0 15.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.004 0.063 -9999.0 0.0 -0.504 1.0 1.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.042 0.125 -9999.0 0.0 -0.298 9.0 9.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.025 0.106 -9999.0 0.0 -0.374 2.0 2.0 FYN -0.042 0.115 -9999.0 0.0 -0.285 9.0 9.0 mol:Ca2+ -0.042 0.124 -9999.0 0.0 -0.296 9.0 9.0 mol:DAG -0.042 0.124 -9999.0 0.0 -0.297 9.0 9.0 NPHS2 -0.017 0.077 -9999.0 0.0 -0.432 2.0 2.0 mol:IP3 -0.042 0.124 -9999.0 0.0 -0.297 9.0 9.0 regulation of endocytosis -0.036 0.12 -9999.0 0.0 -0.374 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.05 0.124 -9999.0 0.0 -0.305 9.0 9.0 establishment of cell polarity -0.067 0.157 -9999.0 0.0 -0.346 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 -0.03 0.115 -9999.0 0.0 -0.41 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 -0.035 0.122 -9999.0 0.0 -0.379 4.0 4.0 NPHS1 -0.058 0.161 -9999.0 0.0 -0.455 9.0 9.0 Nephrin/NEPH1/podocin -0.041 0.116 -9999.0 0.0 -0.287 9.0 9.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.125 -9999.0 0.0 -0.298 9.0 9.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.042 0.125 -9999.0 0.0 -0.298 9.0 9.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.066 0.139 -9999.0 0.0 -0.312 10.0 10.0 cytoskeleton organization -0.029 0.124 -9999.0 0.0 -0.349 5.0 5.0 Nephrin/NEPH1 -0.045 0.112 -9999.0 0.0 -0.277 9.0 9.0 Nephrin/NEPH1/ZO-1 -0.044 0.127 -9999.0 0.0 -0.306 9.0 9.0