Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.231 0.312 0.639 166.0 -9999.0 0.0 166.0 KIRREL -0.057 0.196 -9999.0 0.0 -0.87 25.0 25.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.232 0.313 -9999.0 0.0 -0.641 166.0 166.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.033 -9999.0 0.0 -0.694 1.0 1.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.239 0.299 -9999.0 0.0 -0.629 141.0 141.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.141 0.226 -9999.0 0.0 -0.548 57.0 57.0 FYN -0.209 0.292 -9999.0 0.0 -0.592 141.0 141.0 mol:Ca2+ -0.235 0.291 -9999.0 0.0 -0.617 140.0 140.0 mol:DAG -0.236 0.293 -9999.0 0.0 -0.621 140.0 140.0 NPHS2 -0.152 0.29 -9999.0 0.0 -0.749 88.0 88.0 mol:IP3 -0.236 0.293 -9999.0 0.0 -0.621 140.0 140.0 regulation of endocytosis -0.209 0.263 -9999.0 0.0 -0.712 59.0 59.0 Nephrin/NEPH1/podocin/Cholesterol -0.242 0.299 -9999.0 0.0 -0.634 140.0 140.0 establishment of cell polarity -0.231 0.312 -9999.0 0.0 -0.639 166.0 166.0 Nephrin/NEPH1/podocin/NCK1-2 -0.218 0.274 -9999.0 0.0 -0.756 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.205 0.274 -9999.0 0.0 -0.727 59.0 59.0 NPHS1 -0.249 0.372 -9999.0 0.0 -0.792 148.0 148.0 Nephrin/NEPH1/podocin -0.225 0.283 -9999.0 0.0 -0.596 141.0 141.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.04 -9999.0 0.0 -0.85 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.237 0.295 -9999.0 0.0 -0.625 140.0 140.0 CD2AP 0.011 0.052 -9999.0 0.0 -0.772 2.0 2.0 Nephrin/NEPH1/podocin/GRB2 -0.237 0.295 -9999.0 0.0 -0.625 140.0 140.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.226 0.315 -9999.0 0.0 -0.615 151.0 151.0 cytoskeleton organization -0.186 0.293 -9999.0 0.0 -0.635 92.0 92.0 Nephrin/NEPH1 -0.174 0.239 -9999.0 0.0 -0.483 166.0 166.0 Nephrin/NEPH1/ZO-1 -0.188 0.26 -9999.0 0.0 -0.525 166.0 166.0