Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.036 0.243 -9999.0 0.0 -0.818 26.0 26.0 MAP3K8 0.007 0.073 -9999.0 0.0 -0.772 4.0 4.0 FOS -0.024 0.215 -9999.0 0.0 -0.78 26.0 26.0 PRKCA 0.003 0.089 -9999.0 0.0 -0.716 7.0 7.0 PTPN7 -0.049 0.218 -9999.0 0.0 -0.781 38.0 38.0 HRAS 0.009 0.069 -9999.0 0.0 -0.85 3.0 3.0 PRKCB -0.018 0.162 -9999.0 0.0 -0.827 18.0 18.0 NRAS 0.015 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP -0.003 0.042 -9999.0 0.0 -0.524 3.0 3.0 MAPK3 -0.02 0.189 -9999.0 0.0 -0.717 26.0 26.0 MAP2K1 0.013 0.127 -9999.0 0.0 -0.578 16.0 16.0 ELK1 0.009 0.057 -9999.0 0.0 -0.693 3.0 3.0 BRAF -0.028 0.118 -9999.0 0.0 -0.58 18.0 18.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.006 63.0 63.0 MAPK1 -0.018 0.186 -9999.0 0.0 -0.731 24.0 24.0 RAF1 -0.026 0.113 -9999.0 0.0 -0.585 16.0 16.0 KRAS 0.015 0.001 -9999.0 0.0 -9999.0 0.0 0.0