Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.095 0.192 0.355 147.0 -9999.0 0.0 147.0 KIRREL -0.022 0.121 -9999.0 0.0 -0.573 19.0 19.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.095 0.192 -9999.0 0.0 -0.356 147.0 147.0 PLCG1 0.03 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.03 0.018 -9999.0 0.0 -0.352 1.0 1.0 WASL 0.028 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.074 0.187 -9999.0 0.0 -0.344 121.0 121.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.062 0.137 -9999.0 0.0 -0.316 80.0 80.0 FYN -0.089 0.158 0.286 7.0 -0.317 124.0 131.0 mol:Ca2+ -0.072 0.181 -9999.0 0.0 -0.337 122.0 122.0 mol:DAG -0.072 0.183 -9999.0 0.0 -0.339 122.0 122.0 NPHS2 -0.071 0.162 -9999.0 0.0 -0.394 86.0 86.0 mol:IP3 -0.072 0.183 -9999.0 0.0 -0.339 122.0 122.0 regulation of endocytosis -0.066 0.16 -9999.0 0.0 -0.301 120.0 120.0 Nephrin/NEPH1/podocin/Cholesterol -0.084 0.176 -9999.0 0.0 -0.34 123.0 123.0 establishment of cell polarity -0.095 0.192 -9999.0 0.0 -0.355 147.0 147.0 Nephrin/NEPH1/podocin/NCK1-2 -0.053 0.178 -9999.0 0.0 -0.317 113.0 113.0 Nephrin/NEPH1/beta Arrestin2 -0.066 0.163 -9999.0 0.0 -0.305 120.0 120.0 NPHS1 -0.13 0.23 -9999.0 0.0 -0.459 144.0 144.0 Nephrin/NEPH1/podocin -0.075 0.167 -9999.0 0.0 -0.318 124.0 124.0 TJP1 0.031 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.03 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.071 0.184 -9999.0 0.0 -0.341 121.0 121.0 CD2AP 0.029 0.028 -9999.0 0.0 -0.559 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.073 0.184 -9999.0 0.0 -0.34 123.0 123.0 GRB2 0.031 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.102 0.169 0.298 7.0 -0.33 132.0 139.0 cytoskeleton organization -0.087 0.163 -9999.0 0.0 -0.387 78.0 78.0 Nephrin/NEPH1 -0.062 0.139 -9999.0 0.0 -0.274 116.0 116.0 Nephrin/NEPH1/ZO-1 -0.055 0.166 -9999.0 0.0 -0.354 79.0 79.0