Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.144 0.23 0.456 21.0 -9999.0 0.0 21.0 KIRREL -0.067 0.183 -9999.0 0.0 -0.58 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.144 0.23 -9999.0 0.0 -0.457 21.0 21.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.131 0.224 -9999.0 0.0 -0.596 8.0 8.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.09 0.171 -9999.0 0.0 -0.41 8.0 8.0 FYN -0.124 0.206 -9999.0 0.0 -0.392 19.0 19.0 mol:Ca2+ -0.131 0.221 -9999.0 0.0 -0.589 8.0 8.0 mol:DAG -0.131 0.223 -9999.0 0.0 -0.592 8.0 8.0 NPHS2 -0.098 0.214 -9999.0 0.0 -0.588 10.0 10.0 mol:IP3 -0.131 0.223 -9999.0 0.0 -0.592 8.0 8.0 regulation of endocytosis -0.11 0.196 -9999.0 0.0 -0.511 8.0 8.0 Nephrin/NEPH1/podocin/Cholesterol -0.14 0.224 -9999.0 0.0 -0.397 24.0 24.0 establishment of cell polarity -0.144 0.23 -9999.0 0.0 -0.456 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 -0.113 0.209 -9999.0 0.0 -0.549 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.111 0.199 -9999.0 0.0 -0.519 8.0 8.0 NPHS1 -0.146 0.255 -9999.0 0.0 -0.582 16.0 16.0 Nephrin/NEPH1/podocin -0.125 0.207 -9999.0 0.0 -0.395 19.0 19.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.131 0.224 -9999.0 0.0 -0.596 8.0 8.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.131 0.224 -9999.0 0.0 -0.596 8.0 8.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.164 0.255 -9999.0 0.0 -0.543 16.0 16.0 cytoskeleton organization -0.11 0.207 -9999.0 0.0 -0.506 8.0 8.0 Nephrin/NEPH1 -0.102 0.169 -9999.0 0.0 -0.328 21.0 21.0 Nephrin/NEPH1/ZO-1 -0.107 0.189 -9999.0 0.0 -0.362 21.0 21.0