Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.058 0.146 0.337 11.0 -9999.0 0.0 11.0 KIRREL -0.039 0.133 -9999.0 0.0 -0.395 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.058 0.146 -9999.0 0.0 -0.338 11.0 11.0 PLCG1 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.012 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.038 0.133 -9999.0 0.0 -0.228 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.05 0.108 -9999.0 0.0 -0.264 11.0 11.0 FYN -0.066 0.112 0.268 2.0 -0.246 12.0 14.0 mol:Ca2+ -0.04 0.131 -9999.0 0.0 -0.258 12.0 12.0 mol:DAG -0.039 0.132 -9999.0 0.0 -0.259 12.0 12.0 NPHS2 -0.043 0.088 -9999.0 0.0 -0.219 10.0 10.0 mol:IP3 -0.039 0.132 -9999.0 0.0 -0.259 12.0 12.0 regulation of endocytosis -0.033 0.114 -9999.0 0.0 -0.237 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.042 0.126 -9999.0 0.0 -0.222 18.0 18.0 establishment of cell polarity -0.058 0.146 -9999.0 0.0 -0.337 11.0 11.0 Nephrin/NEPH1/podocin/NCK1-2 -0.025 0.133 -9999.0 0.0 -0.243 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.033 0.115 -9999.0 0.0 -0.239 11.0 11.0 NPHS1 -0.071 0.143 -9999.0 0.0 -0.29 16.0 16.0 Nephrin/NEPH1/podocin -0.039 0.12 -9999.0 0.0 -0.247 12.0 12.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.133 -9999.0 0.0 -0.26 12.0 12.0 CD2AP 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.034 0.132 -9999.0 0.0 -0.262 11.0 11.0 GRB2 0.025 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.083 0.132 0.277 2.0 -0.267 16.0 18.0 cytoskeleton organization -0.065 0.13 0.19 3.0 -0.309 11.0 14.0 Nephrin/NEPH1 -0.034 0.104 -9999.0 0.0 -0.234 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.031 0.128 -9999.0 0.0 -0.273 11.0 11.0